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Identification of the BRD1 interaction network and its impact on mental disorder risk.
Fryland T, Christensen JH, Pallesen J, Mattheisen M, Palmfeldt J, Bak M, Grove J, Demontis D, Blechingberg J, Ooi HS, Nyegaard M, Hauberg ME, Tommerup N, Gregersen N, Mors O, Corydon TJ, Nielsen AL, Børglum AD. Fryland T, et al. Genome Med. 2016 May 3;8(1):53. doi: 10.1186/s13073-016-0308-x. Genome Med. 2016. PMID: 27142060 Free PMC article.
The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice.
Qvist P, Christensen JH, Vardya I, Rajkumar AP, Mørk A, Paternoster V, Füchtbauer EM, Pallesen J, Fryland T, Dyrvig M, Hauberg ME, Lundsberg B, Fejgin K, Nyegaard M, Jensen K, Nyengaard JR, Mors O, Didriksen M, Børglum AD. Qvist P, et al. Among authors: fryland t. Biol Psychiatry. 2017 Jul 1;82(1):62-76. doi: 10.1016/j.biopsych.2016.08.037. Epub 2016 Sep 15. Biol Psychiatry. 2017. PMID: 27837920
Brain proteome changes in female Brd1+/- mice unmask dendritic spine pathology and show enrichment for schizophrenia risk.
Paternoster V, Svanborg M, Edhager AV, Rajkumar AP, Eickhardt EA, Pallesen J, Grove J, Qvist P, Fryland T, Wegener G, Nyengaard JR, Mors O, Palmfeldt J, Børglum AD, Christensen JH. Paternoster V, et al. Among authors: fryland t. Neurobiol Dis. 2019 Apr;124:479-488. doi: 10.1016/j.nbd.2018.12.011. Epub 2018 Dec 24. Neurobiol Dis. 2019. PMID: 30590179
Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice.
Rajkumar AP, Qvist P, Donskov JG, Lazarus R, Pallesen J, Nava N, Winther G, Liebenberg N, Cour SH, Paternoster V, Fryland T, Palmfeldt J, Fejgin K, Mørk A, Nyegaard M, Pakkenberg B, Didriksen M, Nyengaard JR, Wegener G, Mors O, Christensen JH, Børglum AD. Rajkumar AP, et al. Among authors: fryland t. Transl Psychiatry. 2020 Jul 17;10(1):239. doi: 10.1038/s41398-020-00914-2. Transl Psychiatry. 2020. PMID: 32681022 Free PMC article.
12 results