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From chemical tools to clinical medicines: nonimmunosuppressive cyclophilin inhibitors derived from the cyclosporin and sanglifehrin scaffolds.
Sweeney ZK, Fu J, Wiedmann B. Sweeney ZK, et al. Among authors: fu j. J Med Chem. 2014 Sep 11;57(17):7145-59. doi: 10.1021/jm500223x. Epub 2014 Jun 3. J Med Chem. 2014. PMID: 24831536
Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline.
Lee PS, Lapointe G, Madera AM, Simmons RL, Xu W, Yifru A, Tjandra M, Karur S, Rico A, Thompson K, Bojkovic J, Xie L, Uehara K, Liu A, Shu W, Bellamacina C, McKenney D, Morris L, Tonn GR, Osborne C, Benton BM, McDowell L, Fu J, Sweeney ZK. Lee PS, et al. Among authors: fu j. J Med Chem. 2018 Oct 25;61(20):9360-9370. doi: 10.1021/acs.jmedchem.8b01287. Epub 2018 Oct 3. J Med Chem. 2018. PMID: 30226381
Development of a cyclosporin A derivative with excellent anti-hepatitis C virus potency.
Fu J, Becker C, Cao L, Capparelli M, Denay R, Fujimoto R, Gai Y, Gao Z, Guenat C, Karur S, Kim H, Li W, Li X, Li W, Lochmann T, Lu A, Lu P, Luneau A, Meier N, Mergo W, Ng S, Parker D, Peng Y, Riss B, Rivkin A, Roggo S, Schroeder H, Schuerch F, Simmons RL, Sun F, Sweeney ZK, Tjandra M, Wang M, Wang R, Weiss AH, Wenger N, Wu Q, Xiong X, Xu S, Xu W, Yifru A, Zhao J, Zhou J, Z├╝rcher C, Gallou F. Fu J, et al. Bioorg Med Chem. 2018 Feb 15;26(4):957-969. doi: 10.1016/j.bmc.2017.09.008. Epub 2017 Sep 7. Bioorg Med Chem. 2018. PMID: 28919180
Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
Fu J, Tjandra M, Becker C, Bednarczyk D, Capparelli M, Elling R, Hanna I, Fujimoto R, Furegati M, Karur S, Kasprzyk T, Knapp M, Leung K, Li X, Lu P, Mergo W, Miault C, Ng S, Parker D, Peng Y, Roggo S, Rivkin A, Simmons RL, Wang M, Wiedmann B, Weiss AH, Xiao L, Xie L, Xu W, Yifru A, Yang S, Zhou B, Sweeney ZK. Fu J, et al. J Med Chem. 2014 Oct 23;57(20):8503-16. doi: 10.1021/jm500862r. Epub 2014 Oct 13. J Med Chem. 2014. PMID: 25310383
Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.
Barnes-Seeman D, Boiselle C, Capacci-Daniel C, Chopra R, Hoffmaster K, Jones CT, Kato M, Lin K, Ma S, Pan G, Shu L, Wang J, Whiteman L, Xu M, Zheng R, Fu J. Barnes-Seeman D, et al. Among authors: fu j. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3979-85. doi: 10.1016/j.bmcl.2014.06.031. Epub 2014 Jun 20. Bioorg Med Chem Lett. 2014. PMID: 24986660
Biodegradation and decolourization of methyl red by Aspergillus versicolor LH1.
Hu CY, Cheng HY, Yao XM, Li LZ, Liu HW, Guo WQ, Yan LS, Fu JL. Hu CY, et al. Among authors: fu jl. Prep Biochem Biotechnol. 2020 Nov 23:1-8. doi: 10.1080/10826068.2020.1848868. Online ahead of print. Prep Biochem Biotechnol. 2020. PMID: 33226883
Production of Cardiomyocyte-Like Cells by Fibroblast Reprogramming with Defined Factors.
Bektik E, Fu JD. Bektik E, et al. Among authors: fu jd. Methods Mol Biol. 2021;2239:33-46. doi: 10.1007/978-1-0716-1084-8_3. Methods Mol Biol. 2021. PMID: 33226611
Corrigendum to "FMRP-absence-induced up-regulation of hypothalamic MAP1B expression decreases AgRP level linking with reduces in food intake and body weight" [Neurochem. Int. 140 (2020) 104847].
Long JY, Jiang W, Xia HB, Fu JY, Lu P, Hu F, Feng WC, Sun WW, Gao MM, Yi YH, Long YS. Long JY, et al. Among authors: fu jy. Neurochem Int. 2020 Nov 19:104903. doi: 10.1016/j.neuint.2020.104903. Online ahead of print. Neurochem Int. 2020. PMID: 33223044 No abstract available.
Neurofilament light chain predicts risk of recurrence in cerebral amyloid angiopathy-related intracerebral hemorrhage.
Cheng X, Su Y, Wang Q, Gao F, Ye X, Wang Y, Xia Y, Fu J, Shen Y, Salman RA, Dong Q. Cheng X, et al. Among authors: fu j. Aging (Albany NY). 2020 Nov 18;12. doi: 10.18632/aging.103927. Online ahead of print. Aging (Albany NY). 2020. PMID: 33221749
Glycoconjugates for glucose transporter-mediated cancer-specific targeting and treatment.
Fu J, Yang J, Seeberger PH, Yin J. Fu J, et al. Carbohydr Res. 2020 Nov 12;498:108195. doi: 10.1016/j.carres.2020.108195. Online ahead of print. Carbohydr Res. 2020. PMID: 33220603
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