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Reversal of bone loss in mice by nongenotropic signaling of sex steroids.
Kousteni S, Chen JR, Bellido T, Han L, Ali AA, O'Brien CA, Plotkin L, Fu Q, Mancino AT, Wen Y, Vertino AM, Powers CC, Stewart SA, Ebert R, Parfitt AM, Weinstein RS, Jilka RL, Manolagas SC. Kousteni S, et al. Among authors: fu q. Science. 2002 Oct 25;298(5594):843-6. doi: 10.1126/science.1074935. Science. 2002. PMID: 12399595
Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism.
Bellido T, Ali AA, Plotkin LI, Fu Q, Gubrij I, Roberson PK, Weinstein RS, O'Brien CA, Manolagas SC, Jilka RL. Bellido T, et al. Among authors: fu q. J Biol Chem. 2003 Dec 12;278(50):50259-72. doi: 10.1074/jbc.M307444200. Epub 2003 Oct 1. J Biol Chem. 2003. PMID: 14523023 Free article.
6,504 results