Fu TM - Search Results

1

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.

Fu TM, Li Y, Lu A, Li Z, Vajjhala PR, Cruz AC, Srivastava DB, DiMaio F, Penczek PA, Siegel RM, Stacey KJ, Egelman EH, Wu H. Fu TM, et al. Mol Cell. 2016 Oct 20;64(2):236-250. doi: 10.1016/j.molcel.2016.09.009. Epub 2016 Oct 13. Mol Cell. 2016. PMID: 27746017 Free PMC article.

2

Crystal structure of the F27G AIM2 PYD mutant and similarities of its self-association to DED/DED interactions.

Lu A, Kabaleeswaran V, Fu T, Magupalli VG, Wu H. Lu A, et al. J Mol Biol. 2014 Apr 3;426(7):1420-7. doi: 10.1016/j.jmb.2013.12.029. Epub 2014 Jan 7. J Mol Biol. 2014. PMID: 24406744 Free PMC article.

3

Structural biology of innate immunity.

Yin Q, Fu TM, Li J, Wu H. Yin Q, et al. Among authors: fu tm. Annu Rev Immunol. 2015;33:393-416. doi: 10.1146/annurev-immunol-032414-112258. Epub 2015 Jan 22. Annu Rev Immunol. 2015. PMID: 25622194 Free PMC article. Review.

4

Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.

Ru H, Chambers MG, Fu TM, Tong AB, Liao M, Wu H. Ru H, et al. Among authors: fu tm. Cell. 2015 Nov 19;163(5):1138-1152. doi: 10.1016/j.cell.2015.10.055. Epub 2015 Nov 5. Cell. 2015. PMID: 26548953 Free PMC article.

5

Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.

Fu Q, Fu TM, Cruz AC, Sengupta P, Thomas SK, Wang S, Siegel RM, Wu H, Chou JJ. Fu Q, et al. Among authors: fu tm. Mol Cell. 2016 Feb 18;61(4):602-613. doi: 10.1016/j.molcel.2016.01.009. Epub 2016 Feb 4. Mol Cell. 2016. PMID: 26853147 Free PMC article.

6

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.

Lu A, Li Y, Schmidt FI, Yin Q, Chen S, Fu TM, Tong AB, Ploegh HL, Mao Y, Wu H. Lu A, et al. Among authors: fu tm. Nat Struct Mol Biol. 2016 May;23(5):416-25. doi: 10.1038/nsmb.3199. Epub 2016 Apr 4. Nat Struct Mol Biol. 2016. PMID: 27043298 Free PMC article.

7

Mechanism of ubiquitin transfer promoted by TRAF6.

Fu TM, Shen C, Li Q, Zhang P, Wu H. Fu TM, et al. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1783-1788. doi: 10.1073/pnas.1721788115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432170 Free PMC article.

8

Inflammation NODs to Antagonists of RIP2-XIAP Interaction.

Xia S, Fu TM, Wu H. Xia S, et al. Among authors: fu tm. Mol Cell. 2018 Feb 15;69(4):535-536. doi: 10.1016/j.molcel.2018.02.003. Mol Cell. 2018. PMID: 29452633 Free PMC article.

9

Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.

Li Y, Fu TM, Lu A, Witt K, Ruan J, Shen C, Wu H. Li Y, et al. Among authors: fu tm. Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):10845-10852. doi: 10.1073/pnas.1810524115. Epub 2018 Oct 2. Proc Natl Acad Sci U S A. 2018. PMID: 30279182 Free PMC article.

10

INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling.

Luong P, Hedl M, Yan J, Zuo T, Fu TM, Jiang X, Thiagarajah JR, Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI. Luong P, et al. Among authors: fu tm. Elife. 2018 Oct 25;7:e38539. doi: 10.7554/eLife.38539. Elife. 2018. PMID: 30355448 Free PMC article.

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