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IMU-838, a Developmental DHODH Inhibitor in Phase II for Autoimmune Disease, Shows Anti-SARS-CoV-2 and Broad-Spectrum Antiviral Efficacy In Vitro.
Hahn F, Wangen C, Häge S, Peter AS, Dobler G, Hurst B, Julander J, Fuchs J, Ruzsics Z, Überla K, Jäck HM, Ptak R, Muehler A, Gröppel M, Vitt D, Peelen E, Kohlhof H, Marschall M. Hahn F, et al. Among authors: fuchs j. Viruses. 2020 Dec 5;12(12):1394. doi: 10.3390/v12121394. Viruses. 2020. PMID: 33291455 Free PMC article.
Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants.
Weigang S, Fuchs J, Zimmer G, Schnepf D, Kern L, Beer J, Luxenburger H, Ankerhold J, Falcone V, Kemming J, Hofmann M, Thimme R, Neumann-Haefelin C, Ulferts S, Grosse R, Hornuss D, Tanriver Y, Rieg S, Wagner D, Huzly D, Schwemmle M, Panning M, Kochs G. Weigang S, et al. Among authors: fuchs j. Nat Commun. 2021 Nov 4;12(1):6405. doi: 10.1038/s41467-021-26602-3. Nat Commun. 2021. PMID: 34737266 Free PMC article.
External Quality Assessment of SARS-CoV-2 Sequencing: an ESGMD-SSM Pilot Trial across 15 European Laboratories.
Wegner F, Roloff T, Huber M, Cordey S, Ramette A, Gerth Y, Bertelli C, Stange M, Seth-Smith HMB, Mari A, Leuzinger K, Cerutti L, Harshman K, Xenarios I, Le Mercier P, Bittel P, Neuenschwander S, Opota O, Fuchs J, Panning M, Michel C, Hallin M, Demuyser T, De Mendonca R, Savelkoul P, Dingemans J, van der Veer B, Boers SA, Claas ECJ, Coolen JPM, Melchers WJG, Gunell M, Kallonen T, Vuorinen T, Hakanen AJ, Bernhoff E, Hetland MAK, Golan Berman H, Adar S, Moran-Gilad J, Wolf DG, Leib SL, Nolte O, Kaiser L, Schmutz S, Kufner V, Zaheri M, Trkola A, Aamot HV, Hirsch HH, Greub G, Egli A. Wegner F, et al. Among authors: fuchs j. J Clin Microbiol. 2022 Jan 19;60(1):e0169821. doi: 10.1128/JCM.01698-21. Epub 2021 Nov 10. J Clin Microbiol. 2022. PMID: 34757834 Free PMC article.
Impaired immune response drives age-dependent severity of COVID-19.
Beer J, Crotta S, Breithaupt A, Ohnemus A, Becker J, Sachs B, Kern L, Llorian M, Ebert N, Labroussaa F, Nhu Thao TT, Trueeb BS, Jores J, Thiel V, Beer M, Fuchs J, Kochs G, Wack A, Schwemmle M, Schnepf D. Beer J, et al. Among authors: fuchs j. J Exp Med. 2022 Dec 5;219(12):e20220621. doi: 10.1084/jem.20220621. Epub 2022 Sep 21. J Exp Med. 2022. PMID: 36129445 Free PMC article.
Total escape of SARS-CoV-2 from dual monoclonal antibody therapy in an immunocompromised patient.
Jaki L, Weigang S, Kern L, Kramme S, Wrobel AG, Grawitz AB, Nawrath P, Martin SR, Dähne T, Beer J, Disch M, Kolb P, Gutbrod L, Reuter S, Warnatz K, Schwemmle M, Gamblin SJ, Neumann-Haefelin E, Schnepf D, Welte T, Kochs G, Huzly D, Panning M, Fuchs J. Jaki L, et al. Among authors: fuchs j. Nat Commun. 2023 Apr 10;14(1):1999. doi: 10.1038/s41467-023-37591-w. Nat Commun. 2023. PMID: 37037847 Free PMC article.
SARS-CoV-2 infection dynamics in a MHCI-mismatched lung transplant recipient.
Fuchs J, Karl V, Hettich I, Alvarado J, Eckert D, Jaki L, Kohl AK, Kremser A, Maks A, Terschluse C, Agarwal P, Emmerich F, Fähndrich S, Flügler A, Hornuss D, Kalbhenn J, Kneidinger N, Lau I, Lother A, Moneke I, Schibilsky D, Schygulla E, Venhoff N, Zissel G, Czerny M, Huzly D, Kochs G, Neumann-Haefelin C, Passlick B, Stolz D, Thimme R, Panning M, Hofmann M, Frye BC. Fuchs J, et al. Nat Commun. 2025 Sep 16;16(1):8292. doi: 10.1038/s41467-025-63681-y. Nat Commun. 2025. PMID: 40957936 Free PMC article.
2,020 results