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23 results
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Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway.
Fuerer C, Iggo R. Fuerer C, et al. Gene Ther. 2002 Feb;9(4):270-81. doi: 10.1038/sj.gt.3301651. Gene Ther. 2002. PMID: 11896466
Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954.
Lukashev AN, Fuerer C, Chen MJ, Searle P, Iggo R. Lukashev AN, et al. Among authors: fuerer c. Hum Gene Ther. 2005 Dec;16(12):1473-83. doi: 10.1089/hum.2005.16.1473. Hum Gene Ther. 2005. PMID: 16390278
Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells.
Fuerer C, Homicsko K, Lukashev AN, Pittet AL, Iggo RD. Fuerer C, et al. BMC Cancer. 2006 Oct 4;6:236. doi: 10.1186/1471-2407-6-236. BMC Cancer. 2006. PMID: 17020613 Free PMC article.
5-Fluorocytosine increases the toxicity of Wnt-targeting replicating adenoviruses that express cytosine deaminase as a late gene.
Fuerer C, Iggo R. Fuerer C, et al. Gene Ther. 2004 Jan;11(2):142-51. doi: 10.1038/sj.gt.3302148. Gene Ther. 2004. PMID: 14712298
Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells.
Hu M, Kurobe M, Jeong YJ, Fuerer C, Ghole S, Nusse R, Sylvester KG. Hu M, et al. Among authors: fuerer c. Gastroenterology. 2007 Nov;133(5):1579-91. doi: 10.1053/j.gastro.2007.08.036. Epub 2007 Aug 28. Gastroenterology. 2007. PMID: 17983805
Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility.
Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. Mulligan KA, et al. Among authors: fuerer c. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):370-7. doi: 10.1073/pnas.1119197109. Epub 2011 Dec 27. Proc Natl Acad Sci U S A. 2012. PMID: 22203956 Free PMC article.
Wnt proteins promote bone regeneration.
Minear S, Leucht P, Jiang J, Liu B, Zeng A, Fuerer C, Nusse R, Helms JA. Minear S, et al. Among authors: fuerer c. Sci Transl Med. 2010 Apr 28;2(29):29ra30. doi: 10.1126/scitranslmed.3000231. Sci Transl Med. 2010. PMID: 20427820
Lentiviral vectors to probe and manipulate the Wnt signaling pathway.
Fuerer C, Nusse R. Fuerer C, et al. PLoS One. 2010 Feb 23;5(2):e9370. doi: 10.1371/journal.pone.0009370. PLoS One. 2010. PMID: 20186325 Free PMC article.
Wnt signaling mediates regional specification in the vertebrate face.
Brugmann SA, Goodnough LH, Gregorieff A, Leucht P, ten Berge D, Fuerer C, Clevers H, Nusse R, Helms JA. Brugmann SA, et al. Among authors: fuerer c. Development. 2007 Sep;134(18):3283-95. doi: 10.1242/dev.005132. Epub 2007 Aug 15. Development. 2007. PMID: 17699607
Wnt signaling and stem cell control.
Nusse R, Fuerer C, Ching W, Harnish K, Logan C, Zeng A, ten Berge D, Kalani Y. Nusse R, et al. Among authors: fuerer c. Cold Spring Harb Symp Quant Biol. 2008;73:59-66. doi: 10.1101/sqb.2008.73.035. Epub 2008 Nov 21. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19028988 Review.
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