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Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study.
Tamamura H, Omagari A, Hiramatsu K, Oishi S, Habashita H, Kanamoto T, Gotoh K, Yamamoto N, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: fujii n. Bioorg Med Chem. 2002 May;10(5):1417-26. doi: 10.1016/s0968-0896(01)00419-9. Bioorg Med Chem. 2002. PMID: 11886804
Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: the insertion of an (E)-alkene dipeptide isostere into the betaII'-turn moiety.
Tamamura H, Hiramatsu K, Miyamoto K, Omagari A, Oishi S, Nakashima H, Yamamoto N, Kuroda Y, Nakagawa T, Otaka A, Fujii N. Tamamura H, et al. Among authors: fujii n. Bioorg Med Chem Lett. 2002 Mar 25;12(6):923-8. doi: 10.1016/s0960-894x(02)00041-0. Bioorg Med Chem Lett. 2002. PMID: 11958995
Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.
Tamamura H, Hiramatsu K, Ueda S, Wang Z, Kusano S, Terakubo S, Trent JO, Peiper SC, Yamamoto N, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: fujii n. J Med Chem. 2005 Jan 27;48(2):380-91. doi: 10.1021/jm049429h. J Med Chem. 2005. PMID: 15658852
Identification of minimal sequence for HIV-1 fusion inhibitors.
Nishikawa H, Oishi S, Fujita M, Watanabe K, Tokiwa R, Ohno H, Kodama E, Izumi K, Kajiwara K, Naitoh T, Matsuoka M, Otaka A, Fujii N. Nishikawa H, et al. Among authors: fujii n. Bioorg Med Chem. 2008 Oct 15;16(20):9184-7. doi: 10.1016/j.bmc.2008.09.018. Epub 2008 Sep 10. Bioorg Med Chem. 2008. PMID: 18819810 Free article.
Interaction of an anti-HIV peptide, T22, with gp120 and CD4.
Tamamura H, Otaka A, Murakami T, Ishihara T, Ibuka T, Waki M, Matsumoto A, Yamamoto N, Fujii N. Tamamura H, et al. Among authors: fujii n. Biochem Biophys Res Commun. 1996 Feb 15;219(2):555-9. doi: 10.1006/bbrc.1996.0272. Biochem Biophys Res Commun. 1996. PMID: 8605026
2,051 results