Fujino H - Search Results

1

Macaque CYP2C76 encodes cytochrome P450 enzyme not orthologous to any human isozymes.

Uno Y, Fujino H, Iwasaki K, Utoh M. Uno Y, et al. Among authors: fujino h. Curr Drug Metab. 2010 Feb;11(2):142-52. doi: 10.2174/138920010791110854. Curr Drug Metab. 2010. PMID: 20359284 Review.

2

CYP2C76-mediated species difference in drug metabolism: a comparison of pitavastatin metabolism between monkeys and humans.

Uno Y, Kumano T, Kito G, Nagata R, Kamataki T, Fujino H. Uno Y, et al. Among authors: fujino h. Xenobiotica. 2007 Jan;37(1):30-43. doi: 10.1080/00498250600968275. Xenobiotica. 2007. PMID: 17178632

3

Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors.

Fujino H, Saito T, Tsunenari Y, Kojima J, Sakaeda T. Fujino H, et al. Xenobiotica. 2004 Nov-Dec;34(11-12):961-71. doi: 10.1080/00498250400015319. Xenobiotica. 2004. PMID: 15801541

4

Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: similarities and difference in the metabolism of pitavastatin in monkeys and humans.

Yamada I, Fujino H, Shimada S, Kojima J. Yamada I, et al. Among authors: fujino h. Xenobiotica. 2003 Jul;33(7):789-803. doi: 10.1080/0049825031000121635. Xenobiotica. 2003. PMID: 12893526

5

Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization.

Fujino H, Yamada I, Shimada S, Yoneda M, Kojima J. Fujino H, et al. Xenobiotica. 2003 Jan;33(1):27-41. doi: 10.1080/0049825021000017957. Xenobiotica. 2003. PMID: 12519692

6

Uptake mechanism of pitavastatin, a new inhibitor of HMG-CoA reductase, in rat hepatocytes.

Shimada S, Fujino H, Morikawa T, Moriyasu M, Kojima J. Shimada S, et al. Among authors: fujino h. Drug Metab Pharmacokinet. 2003;18(4):245-51. doi: 10.2133/dmpk.18.245. Drug Metab Pharmacokinet. 2003. PMID: 15618742

7

Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase--effect of cMOAT deficiency on hepatobiliary excretion in rats and of mdr1a/b gene disruption on tissue distribution in mice.

Fujino H, Yamada I, Shimada S, Kojima J. Fujino H, et al. Drug Metab Pharmacokinet. 2002;17(5):449-56. doi: 10.2133/dmpk.17.449. Drug Metab Pharmacokinet. 2002. PMID: 15618696

8

Effect of gemfibrozil on the metabolism of pitavastatin--determining the best animal model for human CYP and UGT activities.

Fujino H, Saito T, Tsunenari Y, Kojima J. Fujino H, et al. Drug Metabol Drug Interact. 2004;20(1-2):25-42. doi: 10.1515/dmdi.2004.20.1-2.25. Drug Metabol Drug Interact. 2004. PMID: 15283301

9

Interaction between fibrates and statins--metabolic interactions with gemfibrozil.

Fujino H, Yamada I, Shimada S, Hirano M, Tsunenari Y, Kojima J. Fujino H, et al. Drug Metabol Drug Interact. 2003;19(3):161-76. doi: 10.1515/dmdi.2003.19.3.161. Drug Metabol Drug Interact. 2003. PMID: 14682608

10

Studies on the interaction between fibrates and statins using human hepatic microsomes.

Fujino H, Shimada S, Yamada I, Hirano M, Tsunenari Y, Kojima J. Fujino H, et al. Arzneimittelforschung. 2003;53(10):701-7. doi: 10.1055/s-0031-1299815. Arzneimittelforschung. 2003. PMID: 14650362

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