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Novel combination therapy for human colon cancer with adenovirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent.
Ogawa N, Fujiwara T, Kagawa S, Nishizaki M, Morimoto Y, Tanida T, Hizuta A, Yasuda T, Roth JA, Tanaka N. Ogawa N, et al. Among authors: fujiwara t. Int J Cancer. 1997 Nov 4;73(3):367-70. doi: 10.1002/(sici)1097-0215(19971104)73:3<367::aid-ijc11>3.0.co;2-a. Int J Cancer. 1997. PMID: 9359484
Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer.
Bouvet M, Ellis LM, Nishizaki M, Fujiwara T, Liu W, Bucana CD, Fang B, Lee JJ, Roth JA. Bouvet M, et al. Among authors: fujiwara t. Cancer Res. 1998 Jun 1;58(11):2288-92. Cancer Res. 1998. PMID: 9622060
Recombinant adenovirus expressing wild-type p53 is antiangiogenic: a proposed mechanism for bystander effect.
Nishizaki M, Fujiwara T, Tanida T, Hizuta A, Nishimori H, Tokino T, Nakamura Y, Bouvet M, Roth JA, Tanaka N. Nishizaki M, et al. Among authors: fujiwara t. Clin Cancer Res. 1999 May;5(5):1015-23. Clin Cancer Res. 1999. PMID: 10353734
Induction of apoptosis in human esophageal cancer cells by sequential transfer of the wild-type p53 and E2F-1 genes: involvement of p53 accumulation via ARF-mediated MDM2 down-regulation.
Itoshima T, Fujiwara T, Waku T, Shao J, Kataoka M, Yarbrough WG, Liu TJ, Roth JA, Tanaka N, Kodama M. Itoshima T, et al. Among authors: fujiwara t. Clin Cancer Res. 2000 Jul;6(7):2851-9. Clin Cancer Res. 2000. PMID: 10914734
Infection of human esophageal cancer cell lines T.Tn and TE8 with adenovirus vector-expressing E2F-1 (Ad-E2F-1) enhanced mRNA and protein expression of ARF and decreased MDM2 protein expression. ...Infection of T.Tn and TE8 cells first with adenovirus-expressing wil …
Infection of human esophageal cancer cell lines T.Tn and TE8 with adenovirus vector-expressing E2F-1 (Ad-E2F-1) enhanced mRNA and pro …
Efficient Cre/loxP site-specific recombination in a HepG2 human liver cell line.
Kobayashi N, Noguchi H, Westerman KA, Matsumura T, Watanabe T, Totsugawa T, Fujiwara T, Leboulch P, Tanaka N. Kobayashi N, et al. Among authors: fujiwara t. Cell Transplant. 2000 Sep-Oct;9(5):737-42. doi: 10.1177/096368970000900525. Cell Transplant. 2000. PMID: 11144976
The present study utilized retroviral transfer of a prototypical immortalizing gene, simian virus 40 large T antigen (SV40Tag), flanked by a pair of loxP recombination targets and adenovirus-mediated Cre/loxP recombination. ...
The present study utilized retroviral transfer of a prototypical immortalizing gene, simian virus 40 large T antigen (SV40Tag), flank …
Antisense-mediated suppression of human heparanase gene expression inhibits pleural dissemination of human cancer cells.
Uno F, Fujiwara T, Takata Y, Ohtani S, Katsuda K, Takaoka M, Ohkawa T, Naomoto Y, Nakajima M, Tanaka N. Uno F, et al. Among authors: fujiwara t. Cancer Res. 2001 Nov 1;61(21):7855-60. Cancer Res. 2001. PMID: 11691803
Increased heparanase expression in T.Tn human esophageal cancer cells and A549 human lung cancer cells after infection with an adenovirus vector expressing the human heparanase gene (Ad-S/hep) was specifically inhibited by simultaneous infection with Ad-AS/hep in a dose-de …
Increased heparanase expression in T.Tn human esophageal cancer cells and A549 human lung cancer cells after infection with an adenov …
p53 inhibits adriamycin-induced down-regulation of cyclin D1 expression in human cancer cells.
Shao J, Teraishi F, Katsuda K, Tanaka N, Fujiwara T. Shao J, et al. Among authors: fujiwara t. Biochem Biophys Res Commun. 2002 Jan 25;290(3):1101-7. doi: 10.1006/bbrc.2001.6314. Biochem Biophys Res Commun. 2002. PMID: 11798189
Adenovirus-mediated p53 gene therapy for human cancer.
Fujiwara T, Kataoka M, Tanaka N. Fujiwara T, et al. Mol Urol. 2000 Summer;4(2):51-4. doi: 10.1089/10915360050138585. Mol Urol. 2000. PMID: 12006242 Review.
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