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TLR4 activates the β-catenin pathway to cause intestinal neoplasia.
Santaolalla R, Sussman DA, Ruiz JR, Davies JM, Pastorini C, España CL, Sotolongo J, Burlingame O, Bejarano PA, Philip S, Ahmed MM, Ko J, Dirisina R, Barrett TA, Shang L, Lira SA, Fukata M, Abreu MT. Santaolalla R, et al. Among authors: fukata m. PLoS One. 2013 May 14;8(5):e63298. doi: 10.1371/journal.pone.0063298. Print 2013. PLoS One. 2013. PMID: 23691015 Free PMC article.
AP-1 activated by toll-like receptors regulates expression of IL-23 p19.
Liu W, Ouyang X, Yang J, Liu J, Li Q, Gu Y, Fukata M, Lin T, He JC, Abreu M, Unkeless JC, Mayer L, Xiong H. Liu W, et al. Among authors: fukata m. J Biol Chem. 2009 Sep 4;284(36):24006-16. doi: 10.1074/jbc.M109.025528. Epub 2009 Jul 10. J Biol Chem. 2009. PMID: 19592489 Free PMC article.
A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis.
Ungaro R, Fukata M, Hsu D, Hernandez Y, Breglio K, Chen A, Xu R, Sotolongo J, Espana C, Zaias J, Elson G, Mayer L, Kosco-Vilbois M, Abreu MT. Ungaro R, et al. Among authors: fukata m. Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1167-79. doi: 10.1152/ajpgi.90496.2008. Epub 2009 Apr 9. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19359427 Free PMC article.
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