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DNA methyltransferase Dnmt1 associates with histone deacetylase activity.
Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T. Fuks F, et al. Nat Genet. 2000 Jan;24(1):88-91. doi: 10.1038/71750. Nat Genet. 2000. PMID: 10615135
BRCA2 associates with acetyltransferase activity when bound to P/CAF.
Fuks F, Milner J, Kouzarides T. Fuks F, et al. Oncogene. 1998 Nov 12;17(19):2531-4. doi: 10.1038/sj.onc.1202475. Oncogene. 1998. PMID: 9824164
The BRCA2 activation domain associates with and is phosphorylated by a cellular protein kinase.
Milner J, Fuks F, Hughes-Davies L, Kouzarides T. Milner J, et al. Among authors: fuks f. Oncogene. 2000 Sep 7;19(38):4441-5. doi: 10.1038/sj.onc.1203793. Oncogene. 2000. PMID: 10980621
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription.
Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T. Fuks F, et al. EMBO J. 2001 May 15;20(10):2536-44. doi: 10.1093/emboj/20.10.2536. EMBO J. 2001. PMID: 11350943 Free PMC article.
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.
Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, Fuks F, Lo Coco F, Kouzarides T, Nervi C, Minucci S, Pelicci PG. Di Croce L, et al. Among authors: fuks f. Science. 2002 Feb 8;295(5557):1079-82. doi: 10.1126/science.1065173. Science. 2002. PMID: 11834837
DNA methyltransferases get connected to chromatin.
Burgers WA, Fuks F, Kouzarides T. Burgers WA, et al. Among authors: fuks f. Trends Genet. 2002 Jun;18(6):275-7. doi: 10.1016/S0168-9525(02)02667-7. Trends Genet. 2002. PMID: 12044346
Dnmt3L is a transcriptional repressor that recruits histone deacetylase.
Deplus R, Brenner C, Burgers WA, Putmans P, Kouzarides T, de Launoit Y, Fuks F. Deplus R, et al. Among authors: fuks f. Nucleic Acids Res. 2002 Sep 1;30(17):3831-8. doi: 10.1093/nar/gkf509. Nucleic Acids Res. 2002. PMID: 12202768 Free PMC article.
The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation.
Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T. Fuks F, et al. J Biol Chem. 2003 Feb 7;278(6):4035-40. doi: 10.1074/jbc.M210256200. Epub 2002 Nov 9. J Biol Chem. 2003. PMID: 12427740
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase.
Fuks F, Hurd PJ, Deplus R, Kouzarides T. Fuks F, et al. Nucleic Acids Res. 2003 May 1;31(9):2305-12. doi: 10.1093/nar/gkg332. Nucleic Acids Res. 2003. PMID: 12711675 Free PMC article.
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.
Hughes-Davies L, Huntsman D, Ruas M, Fuks F, Bye J, Chin SF, Milner J, Brown LA, Hsu F, Gilks B, Nielsen T, Schulzer M, Chia S, Ragaz J, Cahn A, Linger L, Ozdag H, Cattaneo E, Jordanova ES, Schuuring E, Yu DS, Venkitaraman A, Ponder B, Doherty A, Aparicio S, Bentley D, Theillet C, Ponting CP, Caldas C, Kouzarides T. Hughes-Davies L, et al. Among authors: fuks f. Cell. 2003 Nov 26;115(5):523-35. doi: 10.1016/s0092-8674(03)00930-9. Cell. 2003. PMID: 14651845
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