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Neuroregulator RET initiates Peyer's-patch tissue genesis.
Fukuyama S, Kiyono H. Fukuyama S, et al. Immunity. 2007 Apr;26(4):393-5. doi: 10.1016/j.immuni.2007.04.004. Immunity. 2007. PMID: 17459808
A recent paper by Veiga-Fernandes et al. (2007) demonstrates that RET is also involved in the intestinal immune system through the initiation of Peyer's-patch tissue genesis....
A recent paper by Veiga-Fernandes et al. (2007) demonstrates that RET is also involved in the intestinal immune system through the initiatio …
Initiation of NALT organogenesis is independent of the IL-7R, LTbetaR, and NIK signaling pathways but requires the Id2 gene and CD3(-)CD4(+)CD45(+) cells.
Fukuyama S, Hiroi T, Yokota Y, Rennert PD, Yanagita M, Kinoshita N, Terawaki S, Shikina T, Yamamoto M, Kurono Y, Kiyono H. Fukuyama S, et al. Immunity. 2002 Jul;17(1):31-40. doi: 10.1016/s1074-7613(02)00339-4. Immunity. 2002. PMID: 12150889
Initiation of nasopharyngeal-associated lymphoid tissue (NALT) development is independent of the programmed cytokine cascade necessary for the formation of Peyer's patches (PP) and peripheral lymph nodes (PLN), a cytokine cascade which consists of IL-7R, LTalpha1beta2/LTbe …
Initiation of nasopharyngeal-associated lymphoid tissue (NALT) development is independent of the programmed cytokine cascade necessary for t …
IgA class switch occurs in the organized nasopharynx- and gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut.
Shikina T, Hiroi T, Iwatani K, Jang MH, Fukuyama S, Tamura M, Kubo T, Ishikawa H, Kiyono H. Shikina T, et al. Among authors: fukuyama s. J Immunol. 2004 May 15;172(10):6259-64. doi: 10.4049/jimmunol.172.10.6259. J Immunol. 2004. PMID: 15128814
In this report we show the preferential presence of IgM(+)B220(+) and IgA(+)B220(+) cells belonging to pre- and post-IgA isotype class-switched cells in the organized mucosa-associated lymphoid tissues, such as nasopharynx-associated lymphoid tissues, isolated lymphoid follicles, …
In this report we show the preferential presence of IgM(+)B220(+) and IgA(+)B220(+) cells belonging to pre- and post-IgA isotype class-switc …
NALT- versus Peyer's-patch-mediated mucosal immunity.
Kiyono H, Fukuyama S. Kiyono H, et al. Among authors: fukuyama s. Nat Rev Immunol. 2004 Sep;4(9):699-710. doi: 10.1038/nri1439. Nat Rev Immunol. 2004. PMID: 15343369 Free PMC article. Review.
Therefore, a greater understanding of the differences between NALT and other organized lymphoid tissues, such as Peyer's patches, should facilitate the development of nasal vaccines....
Therefore, a greater understanding of the differences between NALT and other organized lymphoid tissues, such as Peyer's patches, sho …
Mucosa-associated lymphoid tissues in the aerodigestive tract: their shared and divergent traits and their importance to the orchestration of the mucosal immune system.
Kunisawa J, Fukuyama S, Kiyono H. Kunisawa J, et al. Among authors: fukuyama s. Curr Mol Med. 2005 Sep;5(6):557-72. doi: 10.2174/1566524054863924. Curr Mol Med. 2005. PMID: 16178767 Review.
Cutting edge: Uniqueness of lymphoid chemokine requirement for the initiation and maturation of nasopharynx-associated lymphoid tissue organogenesis.
Fukuyama S, Nagatake T, Kim DY, Takamura K, Park EJ, Kaisho T, Tanaka N, Kurono Y, Kiyono H. Fukuyama S, et al. J Immunol. 2006 Oct 1;177(7):4276-80. doi: 10.4049/jimmunol.177.7.4276. J Immunol. 2006. PMID: 16982861
CD3(-)CD4(+)CD45(+) inducer cells are required for the initiation of mucosa-associated organogenesis of both nasopharynx-associated lymphoid tissues (NALT) and Peyer's patches (PP) in the aerodigestive tract. ...
CD3(-)CD4(+)CD45(+) inducer cells are required for the initiation of mucosa-associated organogenesis of both nasopharynx-associated lymphoid …
A novel M cell-specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses.
Nochi T, Yuki Y, Matsumura A, Mejima M, Terahara K, Kim DY, Fukuyama S, Iwatsuki-Horimoto K, Kawaoka Y, Kohda T, Kozaki S, Igarashi O, Kiyono H. Nochi T, et al. Among authors: fukuyama s. J Exp Med. 2007 Nov 26;204(12):2789-96. doi: 10.1084/jem.20070607. Epub 2007 Nov 5. J Exp Med. 2007. PMID: 17984304 Free PMC article.
Mucosally ingested and inhaled antigens are taken up by membranous or microfold cells (M cells) in the follicle-associated epithelium of Peyer's patches or nasopharynx-associated lymphoid tissue. ...
Mucosally ingested and inhaled antigens are taken up by membranous or microfold cells (M cells) in the follicle-associated epithelium of Pey …
Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity.
Nagatake T, Fukuyama S, Kim DY, Goda K, Igarashi O, Sato S, Nochi T, Sagara H, Yokota Y, Jetten AM, Kaisho T, Akira S, Mimuro H, Sasakawa C, Fukui Y, Fujihashi K, Akiyama T, Inoue J, Penninger JM, Kunisawa J, Kiyono H. Nagatake T, et al. Among authors: fukuyama s. J Exp Med. 2009 Oct 26;206(11):2351-64. doi: 10.1084/jem.20091436. Epub 2009 Oct 12. J Exp Med. 2009. PMID: 19822644 Free PMC article.
Central Role of Core Binding Factor β2 in Mucosa-Associated Lymphoid Tissue Organogenesis in Mouse.
Nagatake T, Fukuyama S, Sato S, Okura H, Tachibana M, Taniuchi I, Ito K, Shimojou M, Matsumoto N, Suzuki H, Kunisawa J, Kiyono H. Nagatake T, et al. Among authors: fukuyama s. PLoS One. 2015 May 22;10(5):e0127460. doi: 10.1371/journal.pone.0127460. eCollection 2015. PLoS One. 2015. PMID: 26001080 Free PMC article.
Peyer's patches (PPs), nasopharynx-associated lymphoid tissue (NALT), and tear duct-associated lymphoid tissue (TALT) are representative MALT in the small intestine, nasal cavity, and lacrimal sac, respectively. ...
Peyer's patches (PPs), nasopharynx-associated lymphoid tissue (NALT), and tear duct-associated lymphoid tissue (TALT) are representat …
Regulatory role of lymphoid chemokine CCL19 and CCL21 in the control of allergic rhinitis.
Takamura K, Fukuyama S, Nagatake T, Kim DY, Kawamura A, Kawauchi H, Kiyono H. Takamura K, et al. Among authors: fukuyama s. J Immunol. 2007 Nov 1;179(9):5897-906. doi: 10.4049/jimmunol.179.9.5897. J Immunol. 2007. PMID: 17947663
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