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Page 1
The dynamic process of β(2)-adrenergic receptor activation.
Nygaard R, Zou Y, Dror RO, Mildorf TJ, Arlow DH, Manglik A, Pan AC, Liu CW, Fung JJ, Bokoch MP, Thian FS, Kobilka TS, Shaw DE, Mueller L, Prosser RS, Kobilka BK. Nygaard R, et al. Among authors: fung jj. Cell. 2013 Jan 31;152(3):532-42. doi: 10.1016/j.cell.2013.01.008. Cell. 2013. PMID: 23374348 Free PMC article.
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Bokoch MP, Zou Y, Rasmussen SG, Liu CW, Nygaard R, Rosenbaum DM, Fung JJ, Choi HJ, Thian FS, Kobilka TS, Puglisi JD, Weis WI, Pardo L, Prosser RS, Mueller L, Kobilka BK. Bokoch MP, et al. Among authors: fung jj. Nature. 2010 Jan 7;463(7277):108-12. doi: 10.1038/nature08650. Nature. 2010. PMID: 20054398 Free PMC article.
High-resolution crystal structure of human protease-activated receptor 1.
Zhang C, Srinivasan Y, Arlow DH, Fung JJ, Palmer D, Zheng Y, Green HF, Pandey A, Dror RO, Shaw DE, Weis WI, Coughlin SR, Kobilka BK. Zhang C, et al. Among authors: fung jj. Nature. 2012 Dec 20;492(7429):387-92. doi: 10.1038/nature11701. Epub 2012 Dec 9. Nature. 2012. PMID: 23222541 Free PMC article.
A monoclonal antibody for G protein-coupled receptor crystallography.
Day PW, Rasmussen SG, Parnot C, Fung JJ, Masood A, Kobilka TS, Yao XJ, Choi HJ, Weis WI, Rohrer DK, Kobilka BK. Day PW, et al. Among authors: fung jj. Nat Methods. 2007 Nov;4(11):927-9. doi: 10.1038/nmeth1112. Epub 2007 Oct 21. Nat Methods. 2007. PMID: 17952087
Structure-based discovery of beta2-adrenergic receptor ligands.
Kolb P, Rosenbaum DM, Irwin JJ, Fung JJ, Kobilka BK, Shoichet BK. Kolb P, et al. Among authors: fung jj. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6843-8. doi: 10.1073/pnas.0812657106. Epub 2009 Apr 2. Proc Natl Acad Sci U S A. 2009. PMID: 19342484 Free PMC article.
FRET-based measurement of GPCR conformational changes.
Granier S, Kim S, Fung JJ, Bokoch MP, Parnot C. Granier S, et al. Among authors: fung jj. Methods Mol Biol. 2009;552:253-68. doi: 10.1007/978-1-60327-317-6_18. Methods Mol Biol. 2009. PMID: 19513655
Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.
Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, Steyaert J, Weis WI, Kobilka BK. Rasmussen SG, et al. Among authors: fung jj. Nature. 2011 Jan 13;469(7329):175-80. doi: 10.1038/nature09648. Nature. 2011. PMID: 21228869 Free PMC article.
Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.
DeVree BT, Mahoney JP, Vélez-Ruiz GA, Rasmussen SG, Kuszak AJ, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt RA, Pardon E, Steyaert J, Kobilka BK, Sunahara RK. DeVree BT, et al. Among authors: fung jj. Nature. 2016 Jul 7;535(7610):182-6. doi: 10.1038/nature18324. Epub 2016 Jun 29. Nature. 2016. PMID: 27362234 Free PMC article.
757 results