Funnell AP - Search Results

1

ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice.

Kelsey L, Flenniken AM, Qu D, Funnell AP, Pearson R, Zhou YQ, Voronina I, Berberovic Z, Wood G, Newbigging S, Weiss ES, Wong M, Quach I, Yeh SY, Deshwar AR, Scott IC, McKerlie C, Henkelman M, Backx P, Simpson J, Osborne L, Rossant J, Crossley M, Bruneau B, Adamson SL. Kelsey L, et al. Among authors: funnell ap. PLoS Genet. 2013;9(7):e1003612. doi: 10.1371/journal.pgen.1003612. Epub 2013 Jul 11. PLoS Genet. 2013. PMID: 23874215 Free PMC article.

2

The mammalian zinc finger transcription factor Krüppel-like factor 3 (KLF3/BKLF).

Pearson RC, Funnell AP, Crossley M. Pearson RC, et al. Among authors: funnell ap. IUBMB Life. 2011 Feb;63(2):86-93. doi: 10.1002/iub.422. Epub 2011 Feb 24. IUBMB Life. 2011. PMID: 21360637 Free article. Review.

3

Hemophilia B Leyden and once mysterious cis-regulatory mutations.

Funnell AP, Crossley M. Funnell AP, et al. Trends Genet. 2014 Jan;30(1):18-23. doi: 10.1016/j.tig.2013.09.007. Epub 2013 Oct 16. Trends Genet. 2014. PMID: 24138812 Review.

4

Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain.

Lim WF, Burdach J, Funnell AP, Pearson RC, Quinlan KG, Crossley M. Lim WF, et al. Among authors: funnell ap. Nucleic Acids Res. 2016 Apr 20;44(7):3118-30. doi: 10.1093/nar/gkv1380. Epub 2015 Dec 15. Nucleic Acids Res. 2016. PMID: 26673701 Free PMC article.

5

Homo- and heterodimerization in transcriptional regulation.

Funnell AP, Crossley M. Funnell AP, et al. Adv Exp Med Biol. 2012;747:105-21. doi: 10.1007/978-1-4614-3229-6_7. Adv Exp Med Biol. 2012. PMID: 22949114 Review.

6

Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor.

Burdach J, Funnell AP, Mak KS, Artuz CM, Wienert B, Lim WF, Tan LY, Pearson RC, Crossley M. Burdach J, et al. Among authors: funnell ap. Nucleic Acids Res. 2014 Jan;42(1):276-89. doi: 10.1093/nar/gkt895. Epub 2013 Oct 7. Nucleic Acids Res. 2014. PMID: 24106088 Free PMC article.

7

Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch.

Norton LJ, Hallal S, Stout ES, Funnell APW, Pearson RCM, Crossley M, Quinlan KGR. Norton LJ, et al. Sci Rep. 2017 Jun 9;7(1):3137. doi: 10.1038/s41598-017-03289-5. Sci Rep. 2017. PMID: 28600522 Free PMC article.

8

A network of Krüppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo.

Eaton SA, Funnell AP, Sue N, Nicholas H, Pearson RC, Crossley M. Eaton SA, et al. Among authors: funnell ap. J Biol Chem. 2008 Oct 3;283(40):26937-47. doi: 10.1074/jbc.M804831200. Epub 2008 Aug 7. J Biol Chem. 2008. PMID: 18687676 Free PMC article.

9

Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor.

Mak KS, Burdach J, Norton LJ, Pearson RC, Crossley M, Funnell AP. Mak KS, et al. Among authors: funnell ap. Genome Biol. 2014 Apr 30;15(4):R58. doi: 10.1186/gb-2014-15-4-r58. Genome Biol. 2014. PMID: 24946810 Free PMC article.

10

Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing.

Funnell AP, Mak KS, Twine NA, Pelka GJ, Norton LJ, Radziewic T, Power M, Wilkins MR, Bell-Anderson KS, Fraser ST, Perkins AC, Tam PP, Pearson RC, Crossley M. Funnell AP, et al. Mol Cell Biol. 2013 Aug;33(15):2976-87. doi: 10.1128/MCB.00074-13. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716600 Free PMC article.

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