Furet P - Search Results

1

Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805.

Baffert F, Régnier CH, De Pover A, Pissot-Soldermann C, Tavares GA, Blasco F, Brueggen J, Chène P, Drueckes P, Erdmann D, Furet P, Gerspacher M, Lang M, Ledieu D, Nolan L, Ruetz S, Trappe J, Vangrevelinghe E, Wartmann M, Wyder L, Hofmann F, Radimerski T. Baffert F, et al. Among authors: furet p. Mol Cancer Ther. 2010 Jul;9(7):1945-55. doi: 10.1158/1535-7163.MCT-10-0053. Epub 2010 Jun 29. Mol Cancer Ther. 2010. PMID: 20587663

2

Structure-activity relationships and binding model of novel aromatase inhibitors.

Lang M, Batzl C, Furet P, Bowman R, Häusler A, Bhatnagar AS. Lang M, et al. Among authors: furet p. J Steroid Biochem Mol Biol. 1993 Mar;44(4-6):421-8. doi: 10.1016/0960-0760(93)90245-r. J Steroid Biochem Mol Biol. 1993. PMID: 8476755

3

Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines.

Traxler P, Bold G, Frei J, Lang M, Lydon N, Mett H, Buchdunger E, Meyer T, Mueller M, Furet P. Traxler P, et al. Among authors: furet p. J Med Chem. 1997 Oct 24;40(22):3601-16. doi: 10.1021/jm970124v. J Med Chem. 1997. PMID: 9357527

4

Strategies toward the design of novel and selective protein tyrosine kinase inhibitors.

Traxler P, Furet P. Traxler P, et al. Among authors: furet p. Pharmacol Ther. 1999 May-Jun;82(2-3):195-206. doi: 10.1016/s0163-7258(98)00044-8. Pharmacol Ther. 1999. PMID: 10454197 Review.

5

A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines.

Chène P, Fuchs J, Bohn J, García-Echeverría C, Furet P, Fabbro D. Chène P, et al. Among authors: furet p. J Mol Biol. 2000 May 26;299(1):245-53. doi: 10.1006/jmbi.2000.3738. J Mol Biol. 2000. PMID: 10860736

6

New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis.

Bold G, Altmann KH, Frei J, Lang M, Manley PW, Traxler P, Wietfeld B, Brüggen J, Buchdunger E, Cozens R, Ferrari S, Furet P, Hofmann F, Martiny-Baron G, Mestan J, Rösel J, Sills M, Stover D, Acemoglu F, Boss E, Emmenegger R, Lässer L, Masso E, Roth R, Schlachter C, Vetterli W. Bold G, et al. Among authors: furet p. J Med Chem. 2000 Jun 15;43(12):2310-23. doi: 10.1021/jm9909443. J Med Chem. 2000. PMID: 10882357

7

Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53.

García-Echeverría C, Chène P, Blommers MJ, Furet P. García-Echeverría C, et al. Among authors: furet p. J Med Chem. 2000 Aug 24;43(17):3205-8. doi: 10.1021/jm990966p. J Med Chem. 2000. PMID: 10966738 No abstract available.

8

Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.

Soni R, O'Reilly T, Furet P, Muller L, Stephan C, Zumstein-Mecker S, Fretz H, Fabbro D, Chaudhuri B. Soni R, et al. Among authors: furet p. J Natl Cancer Inst. 2001 Mar 21;93(6):436-46. doi: 10.1093/jnci/93.6.436. J Natl Cancer Inst. 2001. PMID: 11259469

9

A new structural class of selective and non-covalent inhibitors of the chymotrypsin-like activity of the 20S proteasome.

García-Echeverría C, Imbach P, France D, Fürst P, Lang M, Noorani AM, Scholz D, Zimmermann J, Furet P. García-Echeverría C, et al. Among authors: furet p. Bioorg Med Chem Lett. 2001 May 21;11(10):1317-9. doi: 10.1016/s0960-894x(01)00205-0. Bioorg Med Chem Lett. 2001. PMID: 11392545

10

Modeling of the binding mode of a non-covalent inhibitor of the 20S proteasome. Application to structure-based analogue design.

Furet P, Imbach P, Fürst P, Lang M, Noorani M, Zimmermann J, García-Echeverria C. Furet P, et al. Bioorg Med Chem Lett. 2001 May 21;11(10):1321-4. doi: 10.1016/s0960-894x(01)00206-2. Bioorg Med Chem Lett. 2001. PMID: 11392546

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