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Regulatory role of thiol isomerases in thrombus formation.

Sharda A, Furie B. Sharda A, et al. Among authors: furie b. Expert Rev Hematol. 2018 May;11(5):437-448. doi: 10.1080/17474086.2018.1452612. Epub 2018 Mar 28. Expert Rev Hematol. 2018. PMID: 29542339 Free PMC article. Review.

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Identification of PDI Substrates by Mechanism-Based Kinetic Trapping.

Eriksson O, Stopa J, Furie B. Eriksson O, et al. Among authors: furie b. Methods Mol Biol. 2019;1967:165-182. doi: 10.1007/978-1-4939-9187-7_10. Methods Mol Biol. 2019. PMID: 31069770

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Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents.

Jasuja R, Passam FH, Kennedy DR, Kim SH, van Hessem L, Lin L, Bowley SR, Joshi SS, Dilks JR, Furie B, Furie BC, Flaumenhaft R. Jasuja R, et al. Among authors: furie b, furie bc. J Clin Invest. 2012 Jun;122(6):2104-13. doi: 10.1172/JCI61228. Epub 2012 May 8. J Clin Invest. 2012. PMID: 22565308 Free PMC article.

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Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans.

Panicot-Dubois L, Thomas GM, Furie BC, Furie B, Lombardo D, Dubois C. Panicot-Dubois L, et al. Among authors: furie b, furie bc. J Clin Invest. 2007 Dec;117(12):3708-19. doi: 10.1172/JCI32655. J Clin Invest. 2007. PMID: 18037996 Free PMC article.

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Tissue factor-bearing microparticles and thrombus formation.

Zwicker JI, Trenor CC 3rd, Furie BC, Furie B. Zwicker JI, et al. Among authors: furie b, furie bc. Arterioscler Thromb Vasc Biol. 2011 Apr;31(4):728-33. doi: 10.1161/ATVBAHA.109.200964. Epub 2011 Jan 20. Arterioscler Thromb Vasc Biol. 2011. PMID: 21252066 Free PMC article. Review.

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How I treat poisoning with vitamin K antagonists.

Schulman S, Furie B. Schulman S, et al. Among authors: furie b. Blood. 2015 Jan 15;125(3):438-42. doi: 10.1182/blood-2014-08-597781. Epub 2014 Nov 6. Blood. 2015. PMID: 25377783

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Targeting protein disulfide isomerase with the flavonoid isoquercetin to improve hypercoagulability in advanced cancer.

Zwicker JI, Schlechter BL, Stopa JD, Liebman HA, Aggarwal A, Puligandla M, Caughey T, Bauer KA, Kuemmerle N, Wong E, Wun T, McLaughlin M, Hidalgo M, Neuberg D, Furie B, Flaumenhaft R; CATIQ Investigators11. Zwicker JI, et al. Among authors: furie b. JCI Insight. 2019 Feb 21;4(4):e125851. doi: 10.1172/jci.insight.125851. eCollection 2019 Feb 21. JCI Insight. 2019. PMID: 30652973 Free PMC article. Clinical Trial.

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Kinetic-based trapping by intervening sequence variants of the active sites of protein-disulfide isomerase identifies platelet protein substrates.

Stopa JD, Baker KM, Grover SP, Flaumenhaft R, Furie B. Stopa JD, et al. Among authors: furie b. J Biol Chem. 2017 Jun 2;292(22):9063-9074. doi: 10.1074/jbc.M116.771832. Epub 2017 Mar 31. J Biol Chem. 2017. PMID: 28364042 Free PMC article.

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Protein disulfide isomerase inhibition blocks thrombin generation in humans by interfering with platelet factor V activation.

Stopa JD, Neuberg D, Puligandla M, Furie B, Flaumenhaft R, Zwicker JI. Stopa JD, et al. Among authors: furie b. JCI Insight. 2017 Jan 12;2(1):e89373. doi: 10.1172/jci.insight.89373. JCI Insight. 2017. PMID: 28097231 Free PMC article. Clinical Trial.

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A substrate-driven allosteric switch that enhances PDI catalytic activity.

Bekendam RH, Bendapudi PK, Lin L, Nag PP, Pu J, Kennedy DR, Feldenzer A, Chiu J, Cook KM, Furie B, Huang M, Hogg PJ, Flaumenhaft R. Bekendam RH, et al. Among authors: furie b. Nat Commun. 2016 Aug 30;7:12579. doi: 10.1038/ncomms12579. Nat Commun. 2016. PMID: 27573496 Free PMC article.

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