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39 results
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Site-specific detection of DNA methylation utilizing mCpG-SEER.
Stains CI, Furman JL, Segal DJ, Ghosh I. Stains CI, et al. Among authors: furman jl. J Am Chem Soc. 2006 Aug 2;128(30):9761-5. doi: 10.1021/ja060681j. J Am Chem Soc. 2006. PMID: 16866532
Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.
Badran AH, Furman JL, Ma AS, Comi TJ, Porter JR, Ghosh I. Badran AH, et al. Among authors: furman jl. Anal Chem. 2011 Sep 15;83(18):7151-7. doi: 10.1021/ac2015239. Epub 2011 Aug 23. Anal Chem. 2011. PMID: 21797230 Free PMC article.
Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.
Furman JL, Mok PW, Badran AH, Ghosh I. Furman JL, et al. J Am Chem Soc. 2011 Aug 17;133(32):12518-27. doi: 10.1021/ja1116606. Epub 2011 May 17. J Am Chem Soc. 2011. PMID: 21520929 Free PMC article.
Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2.
Porter JR, Helmers MR, Wang P, Furman JL, Joy ST, Arora PS, Ghosh I. Porter JR, et al. Among authors: furman jl. Chem Commun (Camb). 2010 Nov 14;46(42):8020-2. doi: 10.1039/c0cc02969f. Epub 2010 Sep 20. Chem Commun (Camb). 2010. PMID: 20856941 Free PMC article.
A turn-on split-luciferase sensor for the direct detection of poly(ADP-ribose) as a marker for DNA repair and cell death.
Furman JL, Mok PW, Shen S, Stains CI, Ghosh I. Furman JL, et al. Chem Commun (Camb). 2011 Jan 7;47(1):397-9. doi: 10.1039/c0cc02229b. Epub 2010 Sep 9. Chem Commun (Camb). 2011. PMID: 20830433
Toward a general approach for RNA-templated hierarchical assembly of split-proteins.
Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Furman JL, et al. J Am Chem Soc. 2010 Aug 25;132(33):11692-701. doi: 10.1021/ja104395b. J Am Chem Soc. 2010. PMID: 20681585 Free PMC article.
A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly.
Stains CI, Furman JL, Porter JR, Rajagopal S, Li Y, Wyatt RT, Ghosh I. Stains CI, et al. Among authors: furman jl. ACS Chem Biol. 2010 Oct 15;5(10):943-52. doi: 10.1021/cb100143m. ACS Chem Biol. 2010. PMID: 20681584 Free PMC article.
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.
Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I. Furman JL, et al. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3748-51. doi: 10.1016/j.bmcl.2009.04.141. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19457665 Free PMC article.
A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes.
Furman JL, Kang M, Choi S, Cao Y, Wold ED, Sun SB, Smider VV, Schultz PG, Kim CH. Furman JL, et al. J Am Chem Soc. 2014 Jun 11;136(23):8411-7. doi: 10.1021/ja502851h. Epub 2014 May 30. J Am Chem Soc. 2014. PMID: 24846839 Free PMC article.
A versatile platform for single- and multiple-unnatural amino acid mutagenesis in Escherichia coli.
Chatterjee A, Sun SB, Furman JL, Xiao H, Schultz PG. Chatterjee A, et al. Among authors: furman jl. Biochemistry. 2013 Mar 12;52(10):1828-37. doi: 10.1021/bi4000244. Epub 2013 Feb 27. Biochemistry. 2013. PMID: 23379331 Free PMC article.
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