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MDM2's dual mRNA binding domains co-ordinate its oncogenic and tumour suppressor activities.
Nucleic Acids Res. 2020 Jul 9;48(12):6775-6787. doi: 10.1093/nar/gkaa431.
Nucleic Acids Res. 2020.
PMID: 32453417
Free PMC article.
p53 mRNA and p53 Protein Structures Have Evolved Independently to Interact with MDM2.
Karakostis K, Ponnuswamy A, Fusée LT, Bailly X, Laguerre L, Worall E, Vojtesek B, Nylander K, Fåhraeus R.
Karakostis K, et al. Among authors: fusee lt.
Mol Biol Evol. 2016 May;33(5):1280-92. doi: 10.1093/molbev/msw012. Epub 2016 Jan 27.
Mol Biol Evol. 2016.
PMID: 26823446
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Alternative Mechanisms of p53 Action During the Unfolded Protein Response.
Fusée LTS, Marín M, Fåhraeus R, López I.
Fusée LTS, et al.
Cancers (Basel). 2020 Feb 10;12(2):401. doi: 10.3390/cancers12020401.
Cancers (Basel). 2020.
PMID: 32050651
Free PMC article.
Review.
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The p53 endoplasmic reticulum stress-response pathway evolved in humans but not in mice via PERK-regulated p53 mRNA structures.
Fusée L, Salomao N, Ponnuswamy A, Wang L, López I, Chen S, Gu X, Polyzoidis S, Vadivel Gnanasundram S, Fahraeus R.
Fusée L, et al.
Cell Death Differ. 2023 Apr;30(4):1072-1081. doi: 10.1038/s41418-023-01127-y. Epub 2023 Feb 22.
Cell Death Differ. 2023.
PMID: 36813920
Free PMC article.
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Testis formation in XX individuals resulting from novel pathogenic variants in Wilms' tumor 1 (WT1) gene.
Eozenou C, Gonen N, Touzon MS, Jorgensen A, Yatsenko SA, Fusee L, Kamel AK, Gellen B, Guercio G, Singh P, Witchel S, Berman AJ, Mainpal R, Totonchi M, Mohseni Meybodi A, Askari M, Merel-Chali T, Bignon-Topalovic J, Migale R, Costanzo M, Marino R, Ramirez P, Perez Garrido N, Berensztein E, Mekkawy MK, Schimenti JC, Bertalan R, Mazen I, McElreavey K, Belgorosky A, Lovell-Badge R, Rajkovic A, Bashamboo A.
Eozenou C, et al. Among authors: fusee l.
Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13680-13688. doi: 10.1073/pnas.1921676117. Epub 2020 Jun 3.
Proc Natl Acad Sci U S A. 2020.
PMID: 32493750
Free PMC article.
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Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies.
Portnoi MF, Dumargne MC, Rojo S, Witchel SF, Duncan AJ, Eozenou C, Bignon-Topalovic J, Yatsenko SA, Rajkovic A, Reyes-Mugica M, Almstrup K, Fusee L, Srivastava Y, Chantot-Bastaraud S, Hyon C, Louis-Sylvestre C, Validire P, de Malleray Pichard C, Ravel C, Christin-Maitre S, Brauner R, Rossetti R, Persani L, Charreau EH, Dain L, Chiauzzi VA, Mazen I, Rouba H, Schluth-Bolard C, MacGowan S, McLean WHI, Patin E, Rajpert-De Meyts E, Jauch R, Achermann JC, Siffroi JP, McElreavey K, Bashamboo A.
Portnoi MF, et al. Among authors: fusee l.
Hum Mol Genet. 2018 Apr 1;27(7):1228-1240. doi: 10.1093/hmg/ddy037.
Hum Mol Genet. 2018.
PMID: 29373757
Free PMC article.
Clinical Trial.
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