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Low-density lipoprotein receptor-deficient hepatocytes differentiated from induced pluripotent stem cells allow familial hypercholesterolemia modeling, CRISPR/Cas-mediated genetic correction, and productive hepatitis C virus infection.
Caron J, Pène V, Tolosa L, Villaret M, Luce E, Fourrier A, Heslan JM, Saheb S, Bruckert E, Gómez-Lechón MJ, Nguyen TH, Rosenberg AR, Weber A, Dubart-Kupperschmitt A. Caron J, et al. Among authors: gomez lechon mj. Stem Cell Res Ther. 2019 Jul 29;10(1):221. doi: 10.1186/s13287-019-1342-6. Stem Cell Res Ther. 2019. PMID: 31358055 Free PMC article.
Regenerative cell therapy for the treatment of hyperbilirubinemic Gunn rats with fresh and frozen human induced pluripotent stem cells-derived hepatic stem cells.
Fourrier A, Delbos F, Menoret S, Collet C, Thi Thuy LT, Myara A, Petit F, Tolosa L, Laplanche S, Gómez-Lechón MJ, Labrune P, Anegon I, Vallier L, Garnier D, Nguyen TH. Fourrier A, et al. Among authors: gomez lechon mj. Xenotransplantation. 2020 Jan;27(1):e12544. doi: 10.1111/xen.12544. Epub 2019 Jul 25. Xenotransplantation. 2020. PMID: 31342573
Predicting drug-induced cholestasis: preclinical models.
Petrov PD, Fernández-Murga ML, López-Riera M, Goméz-Lechón MJ, Castell JV, Jover R. Petrov PD, et al. Among authors: gomez lechon mj. Expert Opin Drug Metab Toxicol. 2018 Jul;14(7):721-738. doi: 10.1080/17425255.2018.1487399. Epub 2018 Jun 20. Expert Opin Drug Metab Toxicol. 2018. PMID: 29888962 Review.
242 results