Göhlmann H - Search Results

1

High-Throughput Gene Expression Profiles to Define Drug Similarity and Predict Compound Activity.

De Wolf H, Cougnaud L, Van Hoorde K, De Bondt A, Wegner JK, Ceulemans H, Göhlmann H. De Wolf H, et al. Among authors: gohlmann h. Assay Drug Dev Technol. 2018 Apr;16(3):162-176. doi: 10.1089/adt.2018.845. Assay Drug Dev Technol. 2018. PMID: 29658791

2

Transcriptional Characterization of Compounds: Lessons Learned from the Public LINCS Data.

De Wolf H, De Bondt A, Turner H, Göhlmann HW. De Wolf H, et al. Among authors: gohlmann hw. Assay Drug Dev Technol. 2016 May;14(4):252-60. doi: 10.1089/adt.2016.715. Assay Drug Dev Technol. 2016. PMID: 27187605 Free PMC article.

3

Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines.

Cox MJ, Jaensch S, Van de Waeter J, Cougnaud L, Seynaeve D, Benalla S, Koo SJ, Van Den Wyngaert I, Neefs JM, Malkov D, Bittremieux M, Steemans M, Peeters PJ, Wegner JK, Ceulemans H, Gustin E, Chong YT, Göhlmann HWH. Cox MJ, et al. Among authors: gohlmann hwh. Sci Rep. 2020 Aug 6;10(1):13262. doi: 10.1038/s41598-020-69354-8. Sci Rep. 2020. PMID: 32764586 Free PMC article.

4

Microarray profiling of DNA extracted from FFPE tissues using SNP 6.0 Affymetrix platform.

Tuefferd M, de Bondt A, Van den Wyngaert I, Talloen W, Göhlmann H. Tuefferd M, et al. Among authors: gohlmann h. Methods Mol Biol. 2011;724:147-60. doi: 10.1007/978-1-61779-055-3_10. Methods Mol Biol. 2011. PMID: 21370012

5

A genetics-led approach defines the drug target landscape of 30 immune-related traits.

Fang H; ULTRA-DD Consortium; De Wolf H, Knezevic B, Burnham KL, Osgood J, Sanniti A, Lledó Lara A, Kasela S, De Cesco S, Wegner JK, Handunnetthi L, McCann FE, Chen L, Sekine T, Brennan PE, Marsden BD, Damerell D, O'Callaghan CA, Bountra C, Bowness P, Sundström Y, Milani L, Berg L, Göhlmann HW, Peeters PJ, Fairfax BP, Sundström M, Knight JC. Fang H, et al. Among authors: gohlmann hw. Nat Genet. 2019 Jul;51(7):1082-1091. doi: 10.1038/s41588-019-0456-1. Epub 2019 Jun 28. Nat Genet. 2019. PMID: 31253980 Free PMC article.

6

Progressive leukoencephalopathy impairs neurobehavioral development in sialin-deficient mice.

Stroobants S, Van Acker NG, Verheijen FW, Goris I, Daneels GF, Schot R, Verbeek E, Knaapen MW, De Bondt A, Göhlmann HW, Crauwels ML, Mancini GM, Andries LJ, Moechars DW, D'Hooge R. Stroobants S, et al. Among authors: gohlmann hw. Exp Neurol. 2017 May;291:106-119. doi: 10.1016/j.expneurol.2017.02.009. Epub 2017 Feb 9. Exp Neurol. 2017. PMID: 28189729 Free article.

7

Weighted similarity-based clustering of chemical structures and bioactivity data in early drug discovery.

Perualila-Tan NJ, Shkedy Z, Talloen W, Göhlmann HW; Quantitative Structure Transcription Assay Relationships (QSTAR) Consortium; Moerbeke MV, Kasim A. Perualila-Tan NJ, et al. Among authors: gohlmann hw. J Bioinform Comput Biol. 2016 Aug;14(4):1650018. doi: 10.1142/S0219720016500189. Epub 2016 Apr 26. J Bioinform Comput Biol. 2016. PMID: 27312313

8

cn.FARMS: a latent variable model to detect copy number variations in microarray data with a low false discovery rate.

Clevert DA, Mitterecker A, Mayr A, Klambauer G, Tuefferd M, De Bondt A, Talloen W, Göhlmann H, Hochreiter S. Clevert DA, et al. Among authors: gohlmann h. Nucleic Acids Res. 2011 Jul;39(12):e79. doi: 10.1093/nar/gkr197. Epub 2011 Apr 12. Nucleic Acids Res. 2011. PMID: 21486749 Free PMC article.

9

Testing for trends in dose-response microarray experiments: a comparison of several testing procedures, multiplicity and resampling-based inference.

Lin D, Shkedy Z, Yekutieli D, Burzykowski T, Göhlmann HW, De Bondt A, Perera T, Geerts T, Bijnens L. Lin D, et al. Among authors: gohlmann hw. Stat Appl Genet Mol Biol. 2007;6:Article26. doi: 10.2202/1544-6115.1283. Epub 2007 Oct 11. Stat Appl Genet Mol Biol. 2007. PMID: 18052909

10

Genome-wide copy number alterations detection in fresh frozen and matched FFPE samples using SNP 6.0 arrays.

Tuefferd M, De Bondt A, Van Den Wyngaert I, Talloen W, Verbeke T, Carvalho B, Clevert DA, Alifano M, Raghavan N, Amaratunga D, Göhlmann H, Broët P, Camilleri-Broët S. Tuefferd M, et al. Among authors: gohlmann h. Genes Chromosomes Cancer. 2008 Nov;47(11):957-64. doi: 10.1002/gcc.20599. Genes Chromosomes Cancer. 2008. PMID: 18663747

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