Göhlmann HW - Search Results

1

Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout.

Versele M, Talloen W, Rockx C, Geerts T, Janssen B, Lavrijssen T, King P, Göhlmann HW, Page M, Perera T. Versele M, et al. Among authors: gohlmann hw. Mol Cancer Ther. 2009 Jul;8(7):1846-55. doi: 10.1158/1535-7163.MCT-08-1029. Epub 2009 Jul 7. Mol Cancer Ther. 2009. PMID: 19584230

2

Microarray profiling of DNA extracted from FFPE tissues using SNP 6.0 Affymetrix platform.

Tuefferd M, de Bondt A, Van den Wyngaert I, Talloen W, Göhlmann H. Tuefferd M, et al. Methods Mol Biol. 2011;724:147-60. doi: 10.1007/978-1-61779-055-3_10. Methods Mol Biol. 2011. PMID: 21370012

3

I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data.

Talloen W, Clevert DA, Hochreiter S, Amaratunga D, Bijnens L, Kass S, Göhlmann HW. Talloen W, et al. Among authors: gohlmann hw. Bioinformatics. 2007 Nov 1;23(21):2897-902. doi: 10.1093/bioinformatics/btm478. Epub 2007 Oct 5. Bioinformatics. 2007. PMID: 17921172

4

Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome.

Aerssens J, Camilleri M, Talloen W, Thielemans L, Göhlmann HW, Van Den Wyngaert I, Thielemans T, De Hoogt R, Andrews CN, Bharucha AE, Carlson PJ, Busciglio I, Burton DD, Smyrk T, Urrutia R, Coulie B. Aerssens J, et al. Among authors: gohlmann hw. Clin Gastroenterol Hepatol. 2008 Feb;6(2):194-205. doi: 10.1016/j.cgh.2007.11.012. Clin Gastroenterol Hepatol. 2008. PMID: 18237869 Free PMC article.

5

Genomic biomarkers for a binary clinical outcome in early drug development microarray experiments.

Van Sanden S, Shkedy Z, Burzykowski T, Göhlmann HW, Talloen W, Bijnens L. Van Sanden S, et al. Among authors: gohlmann hw. J Biopharm Stat. 2012;22(1):72-92. doi: 10.1080/10543406.2010.504906. J Biopharm Stat. 2012. PMID: 22204528

6

Integrating High-Dimensional Transcriptomics and Image Analysis Tools into Early Safety Screening: Proof of Concept for a New Early Drug Development Strategy.

Verbist BM, Verheyen GR, Vervoort L, Crabbe M, Beerens D, Bosmans C, Jaensch S, Osselaer S, Talloen W, Van den Wyngaert I, Van Hecke G, Wuyts D; QSTAR Consortium; Van Goethem F, Göhlmann HW. Verbist BM, et al. Among authors: gohlmann hw. Chem Res Toxicol. 2015 Oct 19;28(10):1914-25. doi: 10.1021/acs.chemrestox.5b00103. Epub 2015 Sep 15. Chem Res Toxicol. 2015. PMID: 26313431 Free article.

7

Weighted similarity-based clustering of chemical structures and bioactivity data in early drug discovery.

Perualila-Tan NJ, Shkedy Z, Talloen W, Göhlmann HW; Quantitative Structure Transcription Assay Relationships (QSTAR) Consortium; Moerbeke MV, Kasim A. Perualila-Tan NJ, et al. Among authors: gohlmann hw. J Bioinform Comput Biol. 2016 Aug;14(4):1650018. doi: 10.1142/S0219720016500189. Epub 2016 Apr 26. J Bioinform Comput Biol. 2016. PMID: 27312313

8

The high-level similarity of some disparate gene expression measures.

Raghavan N, De Bondt AM, Talloen W, Moechars D, Göhlmann HW, Amaratunga D. Raghavan N, et al. Among authors: gohlmann hw. Bioinformatics. 2007 Nov 15;23(22):3032-8. doi: 10.1093/bioinformatics/btm448. Epub 2007 Sep 24. Bioinformatics. 2007. PMID: 17893087

9

Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project.

Verbist B, Klambauer G, Vervoort L, Talloen W; QSTAR Consortium; Shkedy Z, Thas O, Bender A, Göhlmann HW, Hochreiter S. Verbist B, et al. Among authors: gohlmann hw. Drug Discov Today. 2015 May;20(5):505-13. doi: 10.1016/j.drudis.2014.12.014. Epub 2015 Jan 10. Drug Discov Today. 2015. PMID: 25582842 Free article.

10

Quality control of Platinum Spike dataset by probe-level mixed models.

Khamiakova T, Shkedy Z, Amaratunga D, Talloen W, Göhlmann H, Bijnens L, Kasim A. Khamiakova T, et al. Math Biosci. 2014 Feb;248:1-10. doi: 10.1016/j.mbs.2013.11.004. Epub 2013 Dec 1. Math Biosci. 2014. PMID: 24300569

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