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DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.
Schoofs T, Rohde C, Hebestreit K, Klein HU, Göllner S, Schulze I, Lerdrup M, Dietrich N, Agrawal-Singh S, Witten A, Stoll M, Lengfelder E, Hofmann WK, Schlenke P, Büchner T, Hansen K, Berdel WE, Rosenbauer F, Dugas M, Müller-Tidow C. Schoofs T, et al. Among authors: gollner s. Blood. 2013 Jan 3;121(1):178-87. doi: 10.1182/blood-2012-08-448860. Epub 2012 Nov 14. Blood. 2013. PMID: 23152544 Free article.
Increased HDAC1 deposition at hematopoietic promoters in AML and its association with patient survival.
Tickenbrock L, Klein HU, Trento C, Hascher A, Göllner S, Bäumer N, Kuss R, Agrawal S, Bug G, Serve H, Thiede C, Ehninger G, Stadt UZ, McClelland M, Wang Y, Becker A, Koschmieder S, Berdel WE, Dugas M, Müller-Tidow C; Study Alliance Leukemia Group. Tickenbrock L, et al. Among authors: gollner s. Leuk Res. 2011 May;35(5):620-5. doi: 10.1016/j.leukres.2010.11.006. Epub 2010 Dec 22. Leuk Res. 2011. PMID: 21176959
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
Schenk T, Chen WC, Göllner S, Howell L, Jin L, Hebestreit K, Klein HU, Popescu AC, Burnett A, Mills K, Casero RA Jr, Marton L, Woster P, Minden MD, Dugas M, Wang JC, Dick JE, Müller-Tidow C, Petrie K, Zelent A. Schenk T, et al. Among authors: gollner s. Nat Med. 2012 Mar 11;18(4):605-11. doi: 10.1038/nm.2661. Nat Med. 2012. PMID: 22406747 Free PMC article.
MYST2 acetyltransferase expression and Histone H4 Lysine acetylation are suppressed in AML.
Sauer T, Arteaga MF, Isken F, Rohde C, Hebestreit K, Mikesch JH, Stelljes M, Cui C, Zhou F, Göllner S, Bäumer N, Köhler G, Krug U, Thiede C, Ehninger G, Edemir B, Schlenke P, Berdel WE, Dugas M, Müller-Tidow C. Sauer T, et al. Among authors: gollner s. Exp Hematol. 2015 Sep;43(9):794-802.e4. doi: 10.1016/j.exphem.2015.05.010. Epub 2015 Jun 11. Exp Hematol. 2015. PMID: 26072331 Free article.
Controlled stem cell amplification by HOXB4 depends on its unique proline-rich region near the N terminus.
Cusan M, Vegi NM, Mulaw MA, Bamezai S, Kaiser LM, Deshpande AJ, Greif PA, Quintanilla-Fend L, Göllner S, Müller-Tidow C, Humphries KR, Armstrong SA, Hiddemann W, Feuring-Buske M, Buske C. Cusan M, et al. Among authors: gollner s. Blood. 2017 Jan 19;129(3):319-323. doi: 10.1182/blood-2016-04-706978. Epub 2016 Nov 8. Blood. 2017. PMID: 27827825 Free article.
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.
Göllner S, Oellerich T, Agrawal-Singh S, Schenk T, Klein HU, Rohde C, Pabst C, Sauer T, Lerdrup M, Tavor S, Stölzel F, Herold S, Ehninger G, Köhler G, Pan KT, Urlaub H, Serve H, Dugas M, Spiekermann K, Vick B, Jeremias I, Berdel WE, Hansen K, Zelent A, Wickenhauser C, Müller LP, Thiede C, Müller-Tidow C. Göllner S, et al. Nat Med. 2017 Jan;23(1):69-78. doi: 10.1038/nm.4247. Epub 2016 Dec 12. Nat Med. 2017. PMID: 27941792 Free PMC article.
The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.
von Heyking K, Calzada-Wack J, Göllner S, Neff F, Schmidt O, Hensel T, Schirmer D, Fasan A, Esposito I, Müller-Tidow C, Sorensen PH, Burdach S, Richter GHS. von Heyking K, et al. Among authors: gollner s. Mol Oncol. 2017 Sep;11(9):1288-1301. doi: 10.1002/1878-0261.12057. Epub 2017 Aug 21. Mol Oncol. 2017. PMID: 28319320 Free PMC article.
Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia.
Mohr S, Doebele C, Comoglio F, Berg T, Beck J, Bohnenberger H, Alexe G, Corso J, Ströbel P, Wachter A, Beissbarth T, Schnütgen F, Cremer A, Haetscher N, Göllner S, Rouhi A, Palmqvist L, Rieger MA, Schroeder T, Bönig H, Müller-Tidow C, Kuchenbauer F, Schütz E, Green AR, Urlaub H, Stegmaier K, Humphries RK, Serve H, Oellerich T. Mohr S, et al. Among authors: gollner s. Cancer Cell. 2017 Apr 10;31(4):549-562.e11. doi: 10.1016/j.ccell.2017.03.001. Cancer Cell. 2017. PMID: 28399410 Free PMC article.
45 results