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Robust TDT-type candidate-gene association tests.
Zheng G, Freidlin B, Gastwirth JL. Zheng G, et al. Among authors: gastwirth jl. Ann Hum Genet. 2002 Mar;66(Pt 2):145-55. doi: 10.1017/S0003480002001045. Ann Hum Genet. 2002. PMID: 12174218
Related methods have been obtained for a given mode of inheritance (e.g. dominant or recessive). Quite often, however, the true model is unknown and selection of a single method of analysis is problematic, since use of a test optimal for one genetic model usually leads to …
Related methods have been obtained for a given mode of inheritance (e.g. dominant or recessive). Quite often, however, the true model …
Robust genomic control for association studies.
Zheng G, Freidlin B, Gastwirth JL. Zheng G, et al. Among authors: gastwirth jl. Am J Hum Genet. 2006 Feb;78(2):350-6. doi: 10.1086/500054. Epub 2005 Dec 22. Am J Hum Genet. 2006. PMID: 16400614 Free PMC article.
This enables one to estimate any additional variance in the null distribution of statistics. When the underlying genetic model (e.g., recessive, additive, or dominant) is known, genomic control can be applied to the corresponding optimal trend tests. ...
This enables one to estimate any additional variance in the null distribution of statistics. When the underlying genetic model (e.g., …
On estimation of the variance in Cochran-Armitage trend tests for genetic association using case-control studies.
Zheng G, Gastwirth JL. Zheng G, et al. Among authors: gastwirth jl. Stat Med. 2006 Sep 30;25(18):3150-9. doi: 10.1002/sim.2250. Stat Med. 2006. PMID: 16397860
As the variance of the test statistic is a function of unknown parameters, e.g. disease prevalence and allele frequency, it must be estimated. ...
As the variance of the test statistic is a function of unknown parameters, e.g. disease prevalence and allele frequency, it must be e …
Using the Peters--Belson method to measure health care disparities from complex survey data.
Graubard BI, Sowmya Rao R, Gastwirth JL. Graubard BI, et al. Among authors: gastwirth jl. Stat Med. 2005 Sep 15;24(17):2659-68. doi: 10.1002/sim.2135. Stat Med. 2005. PMID: 16118808
The Peters-Belson (PB) method uses regression to assess wage discrimination and can also be used to analyse disparities for a variety of health care issues, e.g. cancer screening. The PB method estimates the proportion of an overall disparity that is not explained by the c …
The Peters-Belson (PB) method uses regression to assess wage discrimination and can also be used to analyse disparities for a variety of hea …