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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1982 3
1983 5
1984 1
1985 3
1986 1
1987 1
1988 1
1989 3
1990 2
1991 2
1992 2
1993 5
1994 6
1995 4
1996 6
1997 4
1999 3
2000 1
2001 2
2002 4
2003 6
2004 5
2005 4
2006 9
2007 8
2008 7
2009 10
2010 6
2011 8
2012 9
2013 9
2014 11
2015 9
2016 8
2017 14
2018 15
2019 18
2020 18
2021 23
2022 24
2023 22
2024 14

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293 results

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Page 1
Ligelizumab for Chronic Spontaneous Urticaria.
Maurer M, Giménez-Arnau AM, Sussman G, Metz M, Baker DR, Bauer A, Bernstein JA, Brehler R, Chu CY, Chung WH, Danilycheva I, Grattan C, Hébert J, Katelaris C, Makris M, Meshkova R, Savic S, Sinclair R, Sitz K, Staubach P, Wedi B, Löffler J, Barve A, Kobayashi K, Hua E, Severin T, Janocha R. Maurer M, et al. Among authors: loffler j. N Engl J Med. 2019 Oct 3;381(14):1321-1332. doi: 10.1056/NEJMoa1900408. N Engl J Med. 2019. PMID: 31577874 Free article. Clinical Trial.
A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity.
Heitmann JS, Bilich T, Tandler C, Nelde A, Maringer Y, Marconato M, Reusch J, Jäger S, Denk M, Richter M, Anton L, Weber LM, Roerden M, Bauer J, Rieth J, Wacker M, Hörber S, Peter A, Meisner C, Fischer I, Löffler MW, Karbach J, Jäger E, Klein R, Rammensee HG, Salih HR, Walz JS. Heitmann JS, et al. Among authors: loffler mw. Nature. 2022 Jan;601(7894):617-622. doi: 10.1038/s41586-021-04232-5. Epub 2021 Nov 23. Nature. 2022. PMID: 34814158 Free PMC article. Clinical Trial.
Nivolumab and ipilimumab in recurrent or refractory cancer of unknown primary: a phase II trial.
Pouyiourou M, Kraft BN, Wohlfromm T, Stahl M, Kubuschok B, Löffler H, Hacker UT, Hübner G, Weiss L, Bitzer M, Ernst T, Schütt P, Hielscher T, Delorme S, Kirchner M, Kazdal D, Ball M, Kluck K, Stenzinger A, Bochtler T, Krämer A. Pouyiourou M, et al. Among authors: loffler h. Nat Commun. 2023 Oct 24;14(1):6761. doi: 10.1038/s41467-023-42400-5. Nat Commun. 2023. PMID: 37875494 Free PMC article. Clinical Trial.
[Tumor vaccines-therapeutic vaccination against cancer].
Rammensee HG, Löffler MW, Walz JS, Bokemeyer C, Haen SP, Gouttefangeas C. Rammensee HG, et al. Among authors: loffler mw. Internist (Berl). 2020 Jul;61(7):690-698. doi: 10.1007/s00108-020-00814-z. Internist (Berl). 2020. PMID: 32462251 Review. German.
These differences can be recognized by the immune system, enabling the destruction of tumor cells by T cells, as was impressively demonstrated by the success of immune checkpoint inhibition, e.g., in malignant melanoma. Many cancers, however, do not respond to this kind of …
These differences can be recognized by the immune system, enabling the destruction of tumor cells by T cells, as was impressively demonstrat …
Phase I/II Multicenter Trial of a Novel Therapeutic Cancer Vaccine, HepaVac-101, for Hepatocellular Carcinoma.
Löffler MW, Gori S, Izzo F, Mayer-Mokler A, Ascierto PA, Königsrainer A, Ma YT, Sangro B, Francque S, Vonghia L, Inno A, Avallone A, Ludwig J, Alcoba DD, Flohr C, Aslan K, Mendrzyk R, Schuster H, Borrelli M, Valmori D, Chaumette T, Heidenreich R, Gouttefangeas C, Forlani G, Tagliamonte M, Fusco C, Penta R, Iñarrairaegui M, Gnad-Vogt U, Reinhardt C, Weinschenk T, Accolla RS, Singh-Jasuja H, Rammensee HG, Buonaguro L. Löffler MW, et al. Clin Cancer Res. 2022 Jun 13;28(12):2555-2566. doi: 10.1158/1078-0432.CCR-21-4424. Clin Cancer Res. 2022. PMID: 35421231 Clinical Trial.
naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation.
Bork F, Greve CL, Youn C, Chen S, N C Leal V, Wang Y, Fischer B, Nasri M, Focken J, Scheurer J, Engels P, Dubbelaar M, Hipp K, Zalat B, Szolek A, Wu MJ, Schittek B, Bugl S, Kufer TA, Löffler MW, Chamaillard M, Skokowa J, Kramer D, Archer NK, Weber ANR. Bork F, et al. Among authors: loffler mw. EMBO Rep. 2024 Jul;25(7):2914-2949. doi: 10.1038/s44319-024-00150-5. Epub 2024 May 23. EMBO Rep. 2024. PMID: 38783164 Free PMC article.
Keratinocytes respond to naRNA with expression of psoriasis-related genes (e.g., IL17, IL36) via atypical NOD2-RIPK signaling. In vivo, naRNA drives temporary skin inflammation, which is drastically ameliorated by genetic ablation of RNA sensing. ...
Keratinocytes respond to naRNA with expression of psoriasis-related genes (e.g., IL17, IL36) via atypical NOD2-RIPK signaling. In viv …
Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency.
Heitmann JS, Tandler C, Marconato M, Nelde A, Habibzada T, Rittig SM, Tegeler CM, Maringer Y, Jaeger SU, Denk M, Richter M, Oezbek MT, Wiesmüller KH, Bauer J, Rieth J, Wacker M, Schroeder SM, Hoenisch Gravel N, Scheid J, Märklin M, Henrich A, Klimovich B, Clar KL, Lutz M, Holzmayer S, Hörber S, Peter A, Meisner C, Fischer I, Löffler MW, Peuker CA, Habringer S, Goetze TO, Jäger E, Rammensee HG, Salih HR, Walz JS. Heitmann JS, et al. Among authors: loffler mw. Nat Commun. 2023 Aug 18;14(1):5032. doi: 10.1038/s41467-023-40758-0. Nat Commun. 2023. PMID: 37596280 Free PMC article. Clinical Trial.
An overview of using fungal DNA for the diagnosis of invasive mycoses.
White PL, Alanio A, Brown L, Cruciani M, Hagen F, Gorton R, Lackner M, Millon L, Morton CO, Rautemaa-Richardson R, Barnes RA, Donnelly JP, Loffler J; Fungal PCR Initiative. White PL, et al. Among authors: loffler j. Expert Rev Mol Diagn. 2022 Feb;22(2):169-184. doi: 10.1080/14737159.2022.2037423. Epub 2022 Feb 16. Expert Rev Mol Diagn. 2022. PMID: 35130460 Review.
EXPERT OPINION: For infections caused by Aspergillus, Candida, and Pneumocystis jirovecii, PCR testing is recommended, and combination with serological testing will likely enhance the diagnosis. For other IFD (e.g. mucormycosis), molecular diagnostics represent the only no …
EXPERT OPINION: For infections caused by Aspergillus, Candida, and Pneumocystis jirovecii, PCR testing is recommended, and combination with …
A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activation.
Rade M, Böhlen S, Neuhaus V, Löffler D, Blumert C, Merz M, Köhl U, Dehmel S, Sewald K, Reiche K. Rade M, et al. Among authors: loffler d. Genome Biol. 2023 Dec 14;24(1):287. doi: 10.1186/s13059-023-03120-7. Genome Biol. 2023. PMID: 38098113 Free PMC article.
These biomarker signatures are a valuable source, e.g., monitoring transcriptional changes during T-cell activation with a reasonable number of genes, annotating T-cell states in single-cell transcriptome studies, or assessing dysregulated functions of human T-cell immunit …
These biomarker signatures are a valuable source, e.g., monitoring transcriptional changes during T-cell activation with a reasonable …
Deep learning trained on lymph node status predicts outcome from gastric cancer histopathology: a retrospective multicentric study.
Muti HS, Röcken C, Behrens HM, Löffler CML, Reitsam NG, Grosser B, Märkl B, Stange DE, Jiang X, Velduizen GP, Truhn D, Ebert MP, Grabsch HI, Kather JN. Muti HS, et al. Among authors: loffler cml. Eur J Cancer. 2023 Nov;194:113335. doi: 10.1016/j.ejca.2023.113335. Epub 2023 Sep 12. Eur J Cancer. 2023. PMID: 37862795 Free article.
293 results