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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1997 1
1999 1
2001 4
2002 5
2003 3
2004 3
2005 3
2006 4
2007 7
2008 2
2009 1
2010 4
2011 3
2012 1
2013 3
2014 3
2015 1
2016 3
2017 4
2018 6
2019 5
2020 8
2021 8
2022 10
2023 3
2024 2

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89 results

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Page 1
Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin.
Suriano F, Vieira-Silva S, Falony G, Roumain M, Paquot A, Pelicaen R, Régnier M, Delzenne NM, Raes J, Muccioli GG, Van Hul M, Cani PD. Suriano F, et al. Among authors: muccioli gg. Microbiome. 2021 Jun 28;9(1):147. doi: 10.1186/s40168-021-01097-8. Microbiome. 2021. PMID: 34183063 Free PMC article.
Given that gut microbes dialogue with the host via different metabolites (e.g., short-chain fatty acids) but also contribute to the regulation of bile acids metabolism, we investigated whether inflammatory markers, bacterial components, bile acids, short-chain fatty acids, …
Given that gut microbes dialogue with the host via different metabolites (e.g., short-chain fatty acids) but also contribute to the r …
Endocannabinoid and Prostanoid Crosstalk in Pain.
Buisseret B, Alhouayek M, Guillemot-Legris O, Muccioli GG. Buisseret B, et al. Among authors: muccioli gg. Trends Mol Med. 2019 Oct;25(10):882-896. doi: 10.1016/j.molmed.2019.04.009. Epub 2019 May 31. Trends Mol Med. 2019. PMID: 31160168 Review.
Key to this connection is the production of the cyclooxygenase (COX) substrate arachidonic acid upon eCB hydrolysis as well as the ability of COX to metabolize the eCBs anandamide (AEA) and 2-arachidonoylglycerol (2-AG) into prostaglandin-ethanolamides (PG-EA) and prostaglandin-g …
Key to this connection is the production of the cyclooxygenase (COX) substrate arachidonic acid upon eCB hydrolysis as well as the ability o …
Growth hormone-releasing peptides.
Ghigo E, Arvat E, Muccioli G, Camanni F. Ghigo E, et al. Among authors: muccioli g. Eur J Endocrinol. 1997 May;136(5):445-60. doi: 10.1530/eje.0.1360445. Eur J Endocrinol. 1997. PMID: 9186261 Review.
The GHRP receptor has recently been cloned and, interestingly, it does not show sequence homology with other G-protein-coupled receptors known so far. This evidence strongly suggests the existence of a natural GHRP-like ligand which, however, has not yet been found. ...
The GHRP receptor has recently been cloned and, interestingly, it does not show sequence homology with other G-protein-coupled recept …
Inflammation-induced cholestasis in cancer cachexia.
Thibaut MM, Sboarina M, Roumain M, Pötgens SA, Neyrinck AM, Destrée F, Gillard J, Leclercq IA, Dachy G, Demoulin JB, Tailleux A, Lestavel S, Rastelli M, Everard A, Cani PD, Porporato PE, Loumaye A, Thissen JP, Muccioli GG, Delzenne NM, Bindels LB. Thibaut MM, et al. Among authors: muccioli gg. J Cachexia Sarcopenia Muscle. 2021 Feb;12(1):70-90. doi: 10.1002/jcsm.12652. Epub 2020 Dec 22. J Cachexia Sarcopenia Muscle. 2021. PMID: 33350058 Free PMC article.
Targeting bile acids using cholestyramine reduced hepatic inflammation, without affecting the hepatobiliary transporters (e.g. tumour necrosis factor alpha signalling via NFkappaB and inflammatory response pathways, normalized enrichment scores of -1.44 and -1.36, all Padj …
Targeting bile acids using cholestyramine reduced hepatic inflammation, without affecting the hepatobiliary transporters (e.g. tumour …
Oxysterols: From cholesterol metabolites to key mediators.
Mutemberezi V, Guillemot-Legris O, Muccioli GG. Mutemberezi V, et al. Among authors: muccioli gg. Prog Lipid Res. 2016 Oct;64:152-169. doi: 10.1016/j.plipres.2016.09.002. Epub 2016 Sep 26. Prog Lipid Res. 2016. PMID: 27687912 Review.
They constitute a large family of lipids (i.e. the oxysterome) involved in a plethora of physiological processes. They can act through GPCR (e.g. EBI2, SMO, CXCR2), nuclear receptors (LXR, ROR, ERalpha) and through transporters or regulatory proteins. ...Their levels are g …
They constitute a large family of lipids (i.e. the oxysterome) involved in a plethora of physiological processes. They can act through GPCR …
COX-2-derived endocannabinoid metabolites as novel inflammatory mediators.
Alhouayek M, Muccioli GG. Alhouayek M, et al. Among authors: muccioli gg. Trends Pharmacol Sci. 2014 Jun;35(6):284-92. doi: 10.1016/j.tips.2014.03.001. Epub 2014 Mar 29. Trends Pharmacol Sci. 2014. PMID: 24684963 Review.
On the contrary, it generates PG analogs, namely PG-glycerol esters (PG-G) for 2-AG and PG-ethanolamides (PG-EA or prostamides) for AEA. Although the formation of these COX-2-derived metabolites of the endocannabinoids has been known for a while, their biological effects r …
On the contrary, it generates PG analogs, namely PG-glycerol esters (PG-G) for 2-AG and PG-ethanolamides (PG-EA or prostamides) for A …
N-acylethanolamine hydrolyzing acid amidase inhibition: tools and potential therapeutic opportunities.
Bottemanne P, Muccioli GG, Alhouayek M. Bottemanne P, et al. Among authors: muccioli gg. Drug Discov Today. 2018 Aug;23(8):1520-1529. doi: 10.1016/j.drudis.2018.03.007. Epub 2018 Mar 19. Drug Discov Today. 2018. PMID: 29567427 Review.
N-acylethanolamines (NAEs) (e.g., N-palmitoylethanolamine, N-arachidonoylethanolamine, N-oleoylethanolamine) are bioactive lipids involved in many physiological processes including pain, inflammation, anxiety, cognition and food intake. ...
N-acylethanolamines (NAEs) (e.g., N-palmitoylethanolamine, N-arachidonoylethanolamine, N-oleoylethanolamine) are bioactive lipids inv …
Lipid nanocapsules for the nose-to-brain delivery of the anti-inflammatory bioactive lipid PGD(2)-G.
Mwema A, Bottemanne P, Paquot A, Ucakar B, Vanvarenberg K, Alhouayek M, Muccioli GG, des Rieux A. Mwema A, et al. Among authors: muccioli gg. Nanomedicine. 2023 Feb;48:102633. doi: 10.1016/j.nano.2022.102633. Epub 2022 Nov 23. Nanomedicine. 2023. PMID: 36435364
Here, prostaglandin D(2)-glycerol ester (PGD(2)-G) was selected to target neuroinflammation. As PGD(2)-G is reported to have a short plasmatic half-life, we propose to use lipid nanocapsules (LNC) as vehicle to safely transport PGD(2)-G to the central nervous …
Here, prostaglandin D(2)-glycerol ester (PGD(2)-G) was selected to target neuroinflammation. As PGD(2)-G is reported to have a …
The endogenous bioactive lipid prostaglandin D2-glycerol ester reduces murine colitis via DP1 and PPARγ receptors.
Alhouayek M, Buisseret B, Paquot A, Guillemot-Legris O, Muccioli GG. Alhouayek M, et al. Among authors: muccioli gg. FASEB J. 2018 Sep;32(9):5000-5011. doi: 10.1096/fj.201701205R. Epub 2018 Apr 9. FASEB J. 2018. PMID: 29630407
Furthermore, we showed that PGD(2)-G is an agonist of the PGD(2) receptor 1 (DP1) and that some of the effects of PGD(2)-G were blocked by antagonism of peroxisome proliferator-activated receptor gamma and DP1. ...-Alhouayek, M., Buisseret, B., Paquot, A., Guillemot …
Furthermore, we showed that PGD(2)-G is an agonist of the PGD(2) receptor 1 (DP1) and that some of the effects of PGD(2)-G wer …
89 results