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Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.
Gandhi L, Rodríguez-Abreu D, Gadgeel S, Esteban E, Felip E, De Angelis F, Domine M, Clingan P, Hochmair MJ, Powell SF, Cheng SY, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Hui R, Garon EB, Boyer M, Rubio-Viqueira B, Novello S, Kurata T, Gray JE, Vida J, Wei Z, Yang J, Raftopoulos H, Pietanza MC, Garassino MC; KEYNOTE-189 Investigators. Gandhi L, et al. Among authors: vida j. N Engl J Med. 2018 May 31;378(22):2078-2092. doi: 10.1056/NEJMoa1801005. Epub 2018 Apr 16. N Engl J Med. 2018. PMID: 29658856 Free article. Clinical Trial.
Metabolic roles of poly(ADP-ribose) polymerases.
Vida A, Márton J, Mikó E, Bai P. Vida A, et al. Semin Cell Dev Biol. 2017 Mar;63:135-143. doi: 10.1016/j.semcdb.2016.12.009. Epub 2016 Dec 21. Semin Cell Dev Biol. 2017. PMID: 28013023 Review.
The metabolic regulatory tasks of poly(ADP-ribose) polymerases (PARPs) are complex, it is based on the regulation of metabolic transcription factors (e.g. SIRT1, nuclear receptors, SREBPs) and certain cellular energy sensors. ...
The metabolic regulatory tasks of poly(ADP-ribose) polymerases (PARPs) are complex, it is based on the regulation of metabolic transcription …
Poly(ADP-Ribose) Polymerases in Aging - Friend or Foe?
Vida A, Abdul-Rahman O, Mikó E, Brunyánszki A, Bai P. Vida A, et al. Curr Protein Pept Sci. 2016;17(7):705-712. doi: 10.2174/1389203717666160419144959. Curr Protein Pept Sci. 2016. PMID: 27090903 Review.
PARP activation helps to maintain genomic integrity through supporting DNA repair systems; however, in parallel these enzymes limit metabolic fitness and make the organism more prone for metabolic diseases. In addition, several other pathways (e.g., proteostasis, nutrient …
PARP activation helps to maintain genomic integrity through supporting DNA repair systems; however, in parallel these enzymes limit metaboli …
Variation in the Content and Composition of Tocols in a Wheat Population.
Tremmel-Bede K, Szentmiklóssy M, Lampi AM, Piironen V, Shewry PR, Vida G, Tömösközi S, Karsai I, Láng L, Bedő Z, Rakszegi M. Tremmel-Bede K, et al. Among authors: vida g. Foods. 2022 May 5;11(9):1343. doi: 10.3390/foods11091343. Foods. 2022. PMID: 35564066 Free PMC article.
We therefore determined the tocol content and composition in the grain of 230 recombinant inbred lines (RILs) of a diverse biparental wheat population (Mv Toborzo/Tommi), showing variation in the total content from 13.69 to 45.18 mug/g d.m. The total content also showed tr …
We therefore determined the tocol content and composition in the grain of 230 recombinant inbred lines (RILs) of a diverse biparental wheat …
Extrapleural Closure of Patent Ductus Arteriosus: How We Do It.
Pradegan N, Muñoz YM, Vida VL, Leon-Wyss JR. Pradegan N, et al. Among authors: vida vl. Braz J Cardiovasc Surg. 2020 Oct 29;35(5):831-833. doi: 10.21470/1678-9741-2019-0473. Braz J Cardiovasc Surg. 2020. PMID: 33118750 Free PMC article.
In fact, it requires short surgical times, grants good exposure of the duct and nearby structures (e.g., thoracic duct, left recurrent laryngeal nerve), and avoids pleural space opening and subsequent pulmonary complications in preterm patients. ...
In fact, it requires short surgical times, grants good exposure of the duct and nearby structures (e.g., thoracic duct, left recurren …
Differential distribution and function of GABABRs in somato-dendritic and axonal compartments of principal cells and interneurons in cortical circuits.
Kulik Á, Booker SA, Vida I. Kulik Á, et al. Among authors: vida i. Neuropharmacology. 2018 Jul 1;136(Pt A):80-91. doi: 10.1016/j.neuropharm.2017.10.018. Epub 2017 Oct 14. Neuropharmacology. 2018. PMID: 29042314 Free article. Review.
Whole-cell recordings further demonstrated that GABA(B)Rs differentially mediate post- and presynaptic inhibition in principal cells and various GABAergic interneurons by preferentially modulating postsynaptic G-protein-coupled inwardly rectifying K(+) (Kir3) channels and …
Whole-cell recordings further demonstrated that GABA(B)Rs differentially mediate post- and presynaptic inhibition in principal cells and var …
Antifungal and Anti-Biofilm Effects of Caffeic Acid Phenethyl Ester on Different Candida Species.
Alfarrayeh I, Pollák E, Czéh Á, Vida A, Das S, Papp G. Alfarrayeh I, et al. Among authors: vida a. Antibiotics (Basel). 2021 Nov 7;10(11):1359. doi: 10.3390/antibiotics10111359. Antibiotics (Basel). 2021. PMID: 34827297 Free PMC article.
Our results showed a strain- and dose-dependent effect of CAPE on Candida, and the MIC values were between 12.5 and 100 g/mL. Similarly, the MBIC values of CAPE ranging between 50 and 100 g/mL highlighted the inhibition of the biofilm-forming abilities in a dose-dep …
Our results showed a strain- and dose-dependent effect of CAPE on Candida, and the MIC values were between 12.5 and 100 g/mL. Similar …
Stability analysis of wheat lines with increased level of arabinoxylan.
Tremmel-Bede K, Szentmiklóssy M, Tömösközi S, Török K, Lovegrove A, Shewry PR, Láng L, Bedő Z, Vida G, Rakszegi M. Tremmel-Bede K, et al. Among authors: vida g. PLoS One. 2020 May 8;15(5):e0232892. doi: 10.1371/journal.pone.0232892. eCollection 2020. PLoS One. 2020. PMID: 32384107 Free PMC article.
The stability and heritability of different traits, including the relative effects of the genotype (G) and environment (E), were determined focusing on grain composition. The contents of total and water-soluble pentosans were significantly affected by G, E and G
The stability and heritability of different traits, including the relative effects of the genotype (G) and environment (E), were dete …
Multiple Fungal Metabolites Including Mycotoxins in Naturally Infected and Fusarium-Inoculated Wheat Samples.
Spanic V, Katanic Z, Sulyok M, Krska R, Puskas K, Vida G, Drezner G, Šarkanj B. Spanic V, et al. Among authors: vida g. Microorganisms. 2020 Apr 17;8(4):578. doi: 10.3390/microorganisms8040578. Microorganisms. 2020. PMID: 32316403 Free PMC article.
The most abundant mycotoxins in the inoculated and naturally contaminated samples, respectively, were found to occur at the following average concentrations: DON (19,122/1504 g/kg), CULM (6109/1010 g/kg), 15-hydroxyculmorin (56,022/1301 g/kg), 5-hydroxyculmor …
The most abundant mycotoxins in the inoculated and naturally contaminated samples, respectively, were found to occur at the following averag …
50 results