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Page 1
Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer.
Gandhi L, Rodríguez-Abreu D, Gadgeel S, Esteban E, Felip E, De Angelis F, Domine M, Clingan P, Hochmair MJ, Powell SF, Cheng SY, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Hui R, Garon EB, Boyer M, Rubio-Viqueira B, Novello S, Kurata T, Gray JE, Vida J, Wei Z, Yang J, Raftopoulos H, Pietanza MC, Garassino MC; KEYNOTE-189 Investigators. Gandhi L, et al. Among authors: vida j. N Engl J Med. 2018 May 31;378(22):2078-2092. doi: 10.1056/NEJMoa1801005. Epub 2018 Apr 16. N Engl J Med. 2018. PMID: 29658856 Free article. Clinical Trial.
Metabolic roles of poly(ADP-ribose) polymerases.
Vida A, Márton J, Mikó E, Bai P. Vida A, et al. Semin Cell Dev Biol. 2017 Mar;63:135-143. doi: 10.1016/j.semcdb.2016.12.009. Epub 2016 Dec 21. Semin Cell Dev Biol. 2017. PMID: 28013023 Review.
The metabolic regulatory tasks of poly(ADP-ribose) polymerases (PARPs) are complex, it is based on the regulation of metabolic transcription factors (e.g. SIRT1, nuclear receptors, SREBPs) and certain cellular energy sensors. PARP over-activation can cause damage to mitoch …
The metabolic regulatory tasks of poly(ADP-ribose) polymerases (PARPs) are complex, it is based on the regulation of metabolic transcription …
Unlocking the potential of Molecular Tumor Boards: from cutting-edge data interpretation to innovative clinical pathways.
Pastò B, Buzzatti G, Schettino C, Malapelle U, Bergamini A, De Angelis C, Musacchio L, Dieci MV, Kuhn E, Lambertini M, Passarelli A, Toss A, Farolfi A, Roncato R, Capoluongo E, Vida R, Pignata S, Callari M, Baldassarre G, Bartoletti M, Gerratana L, Puglisi F. Pastò B, et al. Among authors: vida r. Crit Rev Oncol Hematol. 2024 Jul;199:104379. doi: 10.1016/j.critrevonc.2024.104379. Epub 2024 May 7. Crit Rev Oncol Hematol. 2024. PMID: 38718940 Free article. Review.
Poly(ADP-Ribose) Polymerases in Aging - Friend or Foe?
Vida A, Abdul-Rahman O, Mikó E, Brunyánszki A, Bai P. Vida A, et al. Curr Protein Pept Sci. 2016;17(7):705-712. doi: 10.2174/1389203717666160419144959. Curr Protein Pept Sci. 2016. PMID: 27090903 Review.
PARP activation helps to maintain genomic integrity through supporting DNA repair systems; however, in parallel these enzymes limit metabolic fitness and make the organism more prone for metabolic diseases. In addition, several other pathways (e.g., proteostasis, nutrient …
PARP activation helps to maintain genomic integrity through supporting DNA repair systems; however, in parallel these enzymes limit metaboli …
Variation in the Content and Composition of Tocols in a Wheat Population.
Tremmel-Bede K, Szentmiklóssy M, Lampi AM, Piironen V, Shewry PR, Vida G, Tömösközi S, Karsai I, Láng L, Bedő Z, Rakszegi M. Tremmel-Bede K, et al. Among authors: vida g. Foods. 2022 May 5;11(9):1343. doi: 10.3390/foods11091343. Foods. 2022. PMID: 35564066 Free PMC article.
We therefore determined the tocol content and composition in the grain of 230 recombinant inbred lines (RILs) of a diverse biparental wheat population (Mv Toborzo/Tommi), showing variation in the total content from 13.69 to 45.18 mug/g d.m. The total content also showed tr …
We therefore determined the tocol content and composition in the grain of 230 recombinant inbred lines (RILs) of a diverse biparental wheat …
Differential distribution and function of GABABRs in somato-dendritic and axonal compartments of principal cells and interneurons in cortical circuits.
Kulik Á, Booker SA, Vida I. Kulik Á, et al. Among authors: vida i. Neuropharmacology. 2018 Jul 1;136(Pt A):80-91. doi: 10.1016/j.neuropharm.2017.10.018. Epub 2017 Oct 14. Neuropharmacology. 2018. PMID: 29042314 Free article. Review.
Whole-cell recordings further demonstrated that GABA(B)Rs differentially mediate post- and presynaptic inhibition in principal cells and various GABAergic interneurons by preferentially modulating postsynaptic G-protein-coupled inwardly rectifying K(+) (Kir3) channels and …
Whole-cell recordings further demonstrated that GABA(B)Rs differentially mediate post- and presynaptic inhibition in principal cells and var …
Probing the Interactions of 31 Mycotoxins with Xanthine Oxidase: Alternariol, Alternariol-3-Sulfate, and α-Zearalenol Are Allosteric Inhibitors of the Enzyme.
Balázs O, Dombi Á, Zsidó BZ, Hetényi C, Vida RG, Poór M. Balázs O, et al. Among authors: vida rg. Toxins (Basel). 2023 Mar 29;15(4):250. doi: 10.3390/toxins15040250. Toxins (Basel). 2023. PMID: 37104188 Free PMC article.
Interactions of mycotoxins with biotransformation enzymes (e.g., cytochrome P450 enzymes, sulfotransferases, and uridine 5'-diphospho-glucuronosyltransferases) may be important due to their possible detoxification or toxic activation during enzymatic processes. ...
Interactions of mycotoxins with biotransformation enzymes (e.g., cytochrome P450 enzymes, sulfotransferases, and uridine 5'-diphospho …
[Clinically relevant sepsis model in minipigs].
Zsikai B, Bizánc L, Sztányi P, Vida G, Nagy E, Jiga L, Ionac M, Erces D, Boros M, Kaszaki J. Zsikai B, et al. Among authors: vida g. Magy Seb. 2012 Aug;65(4):198-204. doi: 10.1556/MaSeb.65.2012.4.5. Magy Seb. 2012. PMID: 22940388 Hungarian.
MATERIALS AND METHODS: Anesthetized minipigs were subjected to fecal peritonitis (n = 9; 0.5 g/kg i.p. autofeces) or sham-operation (i.p. saline, n = 6). Invasive hemodynamic monitoring was started with regular blood gas analyses between the 15-24 hr of the insult. ...
MATERIALS AND METHODS: Anesthetized minipigs were subjected to fecal peritonitis (n = 9; 0.5 g/kg i.p. autofeces) or sham-operation ( …
Recognition of multiepitope dendrimeric antigens by human immunoglobulin E.
Montañez MI, Najera F, Mayorga C, Ruiz-Sanchez AJ, Vida Y, Collado D, Blanca M, Torres MJ, Perez-Inestrosa E. Montañez MI, et al. Among authors: vida y. Nanomedicine. 2015 Apr;11(3):579-88. doi: 10.1016/j.nano.2015.01.006. Epub 2015 Feb 7. Nanomedicine. 2015. PMID: 25661921
63 results