G0501068/MRC_/Medical Research Council/United Kingdom[Grant Number] - Search Results

Year	Number of Results
2006	2
2007	2
2008	7
2009	5
2010	7
2011	9
2012	7
2013	4
2014	2
2015	4
2016	5
2017	2
2018	1
2019	4
2020	5
2021	4
2022	2
2023	7
2024	1

1

Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex.

Damianou A, Liang Z, Lassen F, Vendrell I, Vere G, Hester S, Charles PD, Pinto-Fernandez A, Santos A, Fischer R, Kessler BM. Damianou A, et al. Life Sci Alliance. 2024 Mar 7;7(5):e202302245. doi: 10.26508/lsa.202302245. Print 2024 May. Life Sci Alliance. 2024. PMID: 38453365 Free PMC article.

2

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.

Gan J, Pinto-Fernández A, Flierman D, Akkermans JJLL, O'Brien DP, Greenwood H, Scott HC, Fritz G, Knobeloch KP, Neefjes J, van Dam H, Ovaa H, Ploegh HL, Kessler BM, Geurink PP, Sapmaz A. Gan J, et al. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2315163120. doi: 10.1073/pnas.2315163120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055744

3

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8⁺ T cell responses.

Wellington D, Yin Z, Yu Z, Heilig R, Davis S, Fischer R, Felce SL, Antoun E, Hublitz P, Beveridge R, Dong D, Liu G, Yao X, Peng Y, Kessler BM, Dong T. Wellington D, et al. Heliyon. 2023 Sep 14;9(10):e20076. doi: 10.1016/j.heliyon.2023.e20076. eCollection 2023 Oct. Heliyon. 2023. PMID: 37842619 Free PMC article.

4

Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma.

Carroll TM, Chadwick JA, Owen RP, White MJ, Kaplinsky J, Peneva I, Frangou A, Xie PF, Chang J, Roth A, Amess B, James SA, Rei M, Fuchs HS, McCann KJ, Omiyale AO, Jacobs BA, Lord SR, Norris-Bulpitt S, Dobbie ST, Griffiths L, Ramirez KA, Ricciardi T, Macri MJ, Ryan A, Venhaus RR, Van den Eynde BJ, Karydis I, Schuster-Böckler B, Middleton MR, Lu X; LUD2015-005 Project Team. Carroll TM, et al. Cancer Cell. 2023 Jul 10;41(7):1222-1241.e7. doi: 10.1016/j.ccell.2023.06.006. Cancer Cell. 2023. PMID: 37433281 Free article.

5

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides.

O'Brien DP, Jones HBL, Guenther F, Murphy EJ, England KS, Vendrell I, Anderson M, Brennan PE, Davis JB, Pinto-Fernández A, Turnbull AP, Kessler BM. O'Brien DP, et al. Mol Cell Proteomics. 2023 Aug;22(8):100609. doi: 10.1016/j.mcpro.2023.100609. Epub 2023 Jun 28. Mol Cell Proteomics. 2023. PMID: 37385347 Free PMC article.

6

USP18 is an essential regulator of muscle cell differentiation and maturation.

Olie CS, Pinto-Fernández A, Damianou A, Vendrell I, Mei H, den Hamer B, van der Wal E, de Greef JC, Raz V, Kessler BM. Olie CS, et al. Cell Death Dis. 2023 Mar 31;14(3):231. doi: 10.1038/s41419-023-05725-z. Cell Death Dis. 2023. PMID: 37002195 Free PMC article.

7

Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.

Dietz L, Ellison CJ, Riechmann C, Cassidy CK, Felfoldi FD, Pinto-Fernández A, Kessler BM, Elliott PR. Dietz L, et al. Science. 2023 Mar 17;379(6637):1112-1117. doi: 10.1126/science.ade8840. Epub 2023 Feb 9. Science. 2023. PMID: 36758106

8

Nilabh Shastri - Towards understanding classical and non-classical MHC-I antigen processing and presentation.

Kessler BM. Kessler BM. Cell Immunol. 2022 Dec;382:104638. doi: 10.1016/j.cellimm.2022.104638. Epub 2022 Nov 8. Cell Immunol. 2022. PMID: 36371991 Free article.

9

Activity-Based Protein Profiling (ABPP) for Cellular Deubiquitinase (DUB) and Inhibitor Profiling at Deep and High-Throughput Levels.

Jones HBL, Heilig R, Kessler BM, Pinto-Fernández A. Jones HBL, et al. Methods Mol Biol. 2023;2591:101-122. doi: 10.1007/978-1-0716-2803-4_7. Methods Mol Biol. 2023. PMID: 36350545

10

Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19.

Vere G, Alam MR, Farrar S, Kealy R, Kessler BM, O'Brien DP, Pinto-Fernández A. Vere G, et al. Biomolecules. 2022 Feb 12;12(2):300. doi: 10.3390/biom12020300. Biomolecules. 2022. PMID: 35204803 Free PMC article. Review.

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