G0800025/MRC_/Medical Research Council/United Kingdom[Grant Number] - Search Results

Year	Number of Results
2007	1
2008	3
2009	2
2010	4
2012	2
2014	1
2022	0

1

Targeting MET in cancer: rationale and progress.

Gherardi E, Birchmeier W, Birchmeier C, Vande Woude G. Gherardi E, et al. Nat Rev Cancer. 2012 Jan 24;12(2):89-103. doi: 10.1038/nrc3205. Nat Rev Cancer. 2012. PMID: 22270953 Review.

2

Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis.

Sinha Roy R, Soni S, Harfouche R, Vasudevan PR, Holmes O, de Jonge H, Rowe A, Paraskar A, Hentschel DM, Chirgadze D, Blundell TL, Gherardi E, Mashelkar RA, Sengupta S. Sinha Roy R, et al. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13608-13. doi: 10.1073/pnas.1006007107. Epub 2010 Jul 16. Proc Natl Acad Sci U S A. 2010. PMID: 20639469 Free PMC article.

3

Crystal structure of an engineered YopM-InlB hybrid protein.

Breitsprecher D, Gherardi E, Bleymüller WM, Niemann HH. Breitsprecher D, et al. BMC Struct Biol. 2014 Mar 27;14:12. doi: 10.1186/1472-6807-14-12. BMC Struct Biol. 2014. PMID: 24669959 Free PMC article.

4

Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB.

Ferraris DM, Gherardi E, Di Y, Heinz DW, Niemann HH. Ferraris DM, et al. J Mol Biol. 2010 Jan 22;395(3):522-32. doi: 10.1016/j.jmb.2009.10.074. Epub 2009 Nov 6. J Mol Biol. 2010. PMID: 19900460 Free article.

5

Structural basis for agonism and antagonism of hepatocyte growth factor.

Tolbert WD, Daugherty-Holtrop J, Gherardi E, Vande Woude G, Xu HE. Tolbert WD, et al. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13264-9. doi: 10.1073/pnas.1005183107. Epub 2010 Jul 12. Proc Natl Acad Sci U S A. 2010. PMID: 20624990 Free PMC article.

6

Engineering the NK1 fragment of hepatocyte growth factor/scatter factor as a MET receptor antagonist.

Youles M, Holmes O, Petoukhov MV, Nessen MA, Stivala S, Svergun DI, Gherardi E. Youles M, et al. J Mol Biol. 2008 Mar 28;377(3):616-22. doi: 10.1016/j.jmb.2008.01.034. Epub 2008 Jan 18. J Mol Biol. 2008. PMID: 18291418

7

Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting.

Wilke S, Krausze J, Gossen M, Groebe L, Jäger V, Gherardi E, van den Heuvel J, Büssow K. Wilke S, et al. Protein Sci. 2010 Jun;19(6):1264-71. doi: 10.1002/pro.390. Protein Sci. 2010. PMID: 20512979 Free PMC article.

8

Engineered variants of InlB with an additional leucine-rich repeat discriminate between physiologically relevant and packing contacts in crystal structures of the InlB:MET complex.

Niemann HH, Gherardi E, Bleymüller WM, Heinz DW. Niemann HH, et al. Protein Sci. 2012 Oct;21(10):1528-39. doi: 10.1002/pro.2142. Epub 2012 Sep 17. Protein Sci. 2012. PMID: 22887347 Free PMC article.

9

A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.

Knudsen BS, Zhao P, Resau J, Cottingham S, Gherardi E, Xu E, Berghuis B, Daugherty J, Grabinski T, Toro J, Giambernardi T, Skinner RS, Gross M, Hudson E, Kort E, Lengyel E, Ventura A, West RA, Xie Q, Hay R, Vande Woude G, Cao B. Knudsen BS, et al. Appl Immunohistochem Mol Morphol. 2009 Jan;17(1):57-67. doi: 10.1097/PAI.0b013e3181816ae2. Appl Immunohistochem Mol Morphol. 2009. PMID: 18815565 Free PMC article.

10

X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB.

Niemann HH, Petoukhov MV, Härtlein M, Moulin M, Gherardi E, Timmins P, Heinz DW, Svergun DI. Niemann HH, et al. J Mol Biol. 2008 Mar 21;377(2):489-500. doi: 10.1016/j.jmb.2008.01.027. Epub 2008 Jan 16. J Mol Biol. 2008. PMID: 18262542

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