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Year Number of Results
2014 4
2015 7
2016 2
2018 1
2021 0
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A primer of NAADP-mediated Ca(2+) signalling: From sea urchin eggs to mammalian cells.
Galione A. Galione A. Cell Calcium. 2015 Jul;58(1):27-47. doi: 10.1016/j.ceca.2014.09.010. Epub 2014 Oct 7. Cell Calcium. 2015. PMID: 25449298 Review.
Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells.
Hamilton A, Zhang Q, Salehi A, Willems M, Knudsen JG, Ringgaard AK, Chapman CE, Gonzalez-Alvarez A, Surdo NC, Zaccolo M, Basco D, Johnson PRV, Ramracheya R, Rutter GA, Galione A, Rorsman P, Tarasov AI. Hamilton A, et al. Diabetes. 2018 Jun;67(6):1128-1139. doi: 10.2337/db17-1102. Epub 2018 Mar 21. Diabetes. 2018. PMID: 29563152 Free PMC article.
Two-Pore Channels: Lessons from Mutant Mouse Models.
Ruas M, Galione A, Parrington J. Ruas M, et al. Messenger (Los Angel). 2015 Jun;4(1):4-22. doi: 10.1166/msr.2015.1041. Messenger (Los Angel). 2015. PMID: 27330869 Free PMC article.
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
Shigeto M, Ramracheya R, Tarasov AI, Cha CY, Chibalina MV, Hastoy B, Philippaert K, Reinbothe T, Rorsman N, Salehi A, Sones WR, Vergari E, Weston C, Gorelik J, Katsura M, Nikolaev VO, Vennekens R, Zaccolo M, Galione A, Johnson PR, Kaku K, Ladds G, Rorsman P. Shigeto M, et al. J Clin Invest. 2015 Dec;125(12):4714-28. doi: 10.1172/JCI81975. Epub 2015 Nov 16. J Clin Invest. 2015. PMID: 26571400 Free PMC article.
Both RyRs and TPCs are required for NAADP-induced intracellular Ca²⁺ release.
Gerasimenko JV, Charlesworth RM, Sherwood MW, Ferdek PE, Mikoshiba K, Parrington J, Petersen OH, Gerasimenko OV. Gerasimenko JV, et al. Cell Calcium. 2015 Sep;58(3):237-45. doi: 10.1016/j.ceca.2015.05.005. Epub 2015 Jun 10. Cell Calcium. 2015. PMID: 26100948 Free PMC article.
Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells.
Ruas M, Davis LC, Chen CC, Morgan AJ, Chuang KT, Walseth TF, Grimm C, Garnham C, Powell T, Platt N, Platt FM, Biel M, Wahl-Schott C, Parrington J, Galione A. Ruas M, et al. EMBO J. 2015 Jul 2;34(13):1743-58. doi: 10.15252/embj.201490009. Epub 2015 Apr 14. EMBO J. 2015. PMID: 25872774 Free PMC article.
VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling.
Favia A, Desideri M, Gambara G, D'Alessio A, Ruas M, Esposito B, Del Bufalo D, Parrington J, Ziparo E, Palombi F, Galione A, Filippini A. Favia A, et al. Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):E4706-15. doi: 10.1073/pnas.1406029111. Epub 2014 Oct 20. Proc Natl Acad Sci U S A. 2014. PMID: 25331892 Free PMC article.
Disallowance of Acot7 in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion.
Martinez-Sanchez A, Pullen TJ, Chabosseau P, Zhang Q, Haythorne E, Cane MC, Nguyen-Tu MS, Sayers SR, Rutter GA. Martinez-Sanchez A, et al. Diabetes. 2016 May;65(5):1268-82. doi: 10.2337/db15-1240. Epub 2016 Feb 9. Diabetes. 2016. PMID: 26861785 Free PMC article.
Identification of a novel gene for diabetic traits in rats, mice, and humans.
Tsaih SW, Holl K, Jia S, Kaldunski M, Tschannen M, He H, Andrae JW, Li SH, Stoddard A, Wiederhold A, Parrington J, Ruas da Silva M, Galione A, Meigs J; Meta-Analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) Investigators, Hoffmann RG, Simpson P, Jacob H, Hessner M, Solberg Woods LC. Tsaih SW, et al. Genetics. 2014 Sep;198(1):17-29. doi: 10.1534/genetics.114.162982. Genetics. 2014. PMID: 25236446 Free PMC article.
The two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca²⁺ dynamics and insulin secretion.
Cane MC, Parrington J, Rorsman P, Galione A, Rutter GA. Cane MC, et al. Cell Calcium. 2016 Jan;59(1):32-40. doi: 10.1016/j.ceca.2015.12.004. Epub 2015 Dec 23. Cell Calcium. 2016. PMID: 26769314 Free PMC article.
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