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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 2
1997 1
1998 1
2000 2
2001 3
2003 1
2004 1
2007 1
2008 1
2009 2
2010 2
2011 1
2012 6
2013 4
2014 5
2015 3
2016 2
2017 2
2018 4
2019 7
2020 2
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Tissue-resident macrophages: then and now.
Davies LC, Taylor PR. Davies LC, et al. Immunology. 2015 Apr;144(4):541-8. doi: 10.1111/imm.12451. Immunology. 2015. PMID: 25684236 Free PMC article. Review.
Macrophages have been at the heart of immune research for over a century and are an integral component of innate immunity. Macrophages are often viewed as terminally differentiated monocytic phagocytes. ...In the last decade, it has been revealed that many of these cells a …
Macrophages have been at the heart of immune research for over a century and are an integral component of innate immunity. Macrophage …
Genetic variations in the transcription factors GATA4 and GATA6 and bleeding complications in patients receiving warfarin therapy.
Yee J, Kim W, Chang BC, Chung JE, Lee KE, Gwak HS. Yee J, et al. Drug Des Devel Ther. 2019 May 17;13:1717-1727. doi: 10.2147/DDDT.S198018. eCollection 2019. Drug Des Devel Ther. 2019. PMID: 31190750 Free PMC article.
The aim of this retrospective study was to investigate the associations between GATA4 and GATA6 polymorphisms and bleeding complication risk at a therapeutic international normalized ratio (INR) in patients with mechanical heart valves. ...Conclusions: This study sh …
The aim of this retrospective study was to investigate the associations between GATA4 and GATA6 polymorphisms and bleeding complicati …
A loss-of-function and H2B-Venus transcriptional reporter allele for Gata6 in mice.
Freyer L, Schröter C, Saiz N, Schrode N, Nowotschin S, Martinez-Arias A, Hadjantonakis AK. Freyer L, et al. BMC Dev Biol. 2015 Oct 24;15:38. doi: 10.1186/s12861-015-0086-5. BMC Dev Biol. 2015. PMID: 26498761 Free PMC article.
CONCLUSIONS: Expression of the Venus reporter was characterized starting from embryonic stem (ES) cells, through mouse embryos and adult animals. ...At early post-implantation stages of embryonic development, there was a strong correlation of Venus with endogenous GATA6
CONCLUSIONS: Expression of the Venus reporter was characterized starting from embryonic stem (ES) cells, through mouse embryos and adult
Familial GATA6 mutation causing variably expressed diabetes mellitus and cardiac and renal abnormalities.
Du YT, Moore L, Poplawski NK, De Sousa SMC. Du YT, et al. Endocrinol Diabetes Metab Case Rep. 2019 May 3;2019:19-0022. doi: 10.1530/EDM-19-0022. Online ahead of print. Endocrinol Diabetes Metab Case Rep. 2019. PMID: 31051468 Free PMC article.
The proband's paternal grandmother had a congenital heart defect. Genetic testing of the proband revealed a novel heterozygous missense variant (Chr18:g.19761441T>C, c.1330T>C, p.Cys444Arg) in exon 4 of GATA6, which is class 5 (pathogenic) using America …
The proband's paternal grandmother had a congenital heart defect. Genetic testing of the proband revealed a novel heterozygous …
Gata4-Dependent Differentiation of c-Kit(+)-Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart.
Maliken BD, Kanisicak O, Karch J, Khalil H, Fu X, Boyer JG, Prasad V, Zheng Y, Molkentin JD. Maliken BD, et al. Circulation. 2018 Sep 4;138(10):1012-1024. doi: 10.1161/CIRCULATIONAHA.118.033703. Circulation. 2018. PMID: 29666070 Free PMC article.
BACKGROUND: Although c-Kit(+) adult progenitor cells were initially reported to produce new cardiomyocytes in the heart, recent genetic evidence suggests that such events are exceedingly rare. ...Deletion of Gata4 from c-Kit(+) endothelial progenitor cells or adu
BACKGROUND: Although c-Kit(+) adult progenitor cells were initially reported to produce new cardiomyocytes in the heart, recen …
GATA6 mutations: Characterization of two novel patients and a comprehensive overview of the GATA6 genotypic and phenotypic spectrum.
Škorić-Milosavljević D, Tjong FVY, Barc J, Backx APCM, Clur SB, van Spaendonck-Zwarts K, Oostra RJ, Lahrouchi N, Beekman L, Bökenkamp R, Barge-Schaapveld DQCM, Mulder BJ, Lodder EM, Bezzina CR, Postma AV. Škorić-Milosavljević D, et al. Am J Med Genet A. 2019 Sep;179(9):1836-1845. doi: 10.1002/ajmg.a.61294. Epub 2019 Jul 12. Am J Med Genet A. 2019. PMID: 31301121 Free PMC article.
The first human mutations in GATA6 were described in a cohort of patients with persistent truncus arteriosus, and the phenotypic spectrum has expanded since then. ...In conclusion, GATA6 mutations give a wide range of phenotypic defects, most frequently malformation …
The first human mutations in GATA6 were described in a cohort of patients with persistent truncus arteriosus, and the phenotypic spec …
Case report: adult onset diabetes with partial pancreatic agenesis and congenital heart disease due to a de novo GATA6 mutation.
Sanchez-Lechuga B, Saqlain M, Ng N, Colclough K, Woods C, Byrne M. Sanchez-Lechuga B, et al. BMC Med Genet. 2020 Apr 3;21(1):70. doi: 10.1186/s12881-020-01012-2. BMC Med Genet. 2020. PMID: 32245430 Free PMC article.
A novel heterozygous pathogenic GATA6 mutation (p.Tyr235Ter) was identified. The GATA6 variant was not detected in her parents, implying that the mutation had arisen de novo in the proband. CONCLUSION: Rarely GATA6 mutations can cause adult onset diabe …
A novel heterozygous pathogenic GATA6 mutation (p.Tyr235Ter) was identified. The GATA6 variant was not detected in her parents …
GATA transcription factors in the developing and adult heart.
Pikkarainen S, Tokola H, Kerkelä R, Ruskoaho H. Pikkarainen S, et al. Cardiovasc Res. 2004 Aug 1;63(2):196-207. doi: 10.1016/j.cardiores.2004.03.025. Cardiovasc Res. 2004. PMID: 15249177 Review.
GATA-4, -5 and -6 are zinc finger transcription factors that are expressed in the developing heart and GATA-4 and -6 continue expression in the adult cardiac myocytes. ...In support of this, mutations of gene for GATA-4 or for its cofactors have been associated with …
GATA-4, -5 and -6 are zinc finger transcription factors that are expressed in the developing heart and GATA-4 and -6 continue express …
Minimal inflammatory foci of unknown etiology may be a tentative sign of early stage inherited cardiomyopathy.
Hata Y, Hirono K, Yamaguchi Y, Ichida F, Oku Y, Nishida N. Hata Y, et al. Mod Pathol. 2019 Sep;32(9):1281-1290. doi: 10.1038/s41379-019-0274-0. Epub 2019 Apr 25. Mod Pathol. 2019. PMID: 31024045 Free article.
Although relatively uncommon, pathologists may encounter minimal inflammatory foci in the absence of typical structural heart disease; however, the clinicopathological significance of minimal inflammatory foci, including correlation with sudden unexpected death, is unexplo …
Although relatively uncommon, pathologists may encounter minimal inflammatory foci in the absence of typical structural heart disease …
Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System.
Paccola Mesquita FC, Hochman-Mendez C, Morrissey J, Sampaio LC, Taylor DA. Paccola Mesquita FC, et al. Stem Cells Int. 2019 Jan 22;2019:9704945. doi: 10.1155/2019/9704945. eCollection 2019. Stem Cells Int. 2019. PMID: 30805013 Free PMC article.
The number of high-quality cells required for engineering an adult human-sized bioartificial organ is greater than one billion. ...Spontaneous differentiation into ectoderm (NESTIN, TUBB3, and NEFH), mesoderm (MSX1, BMP4, and T), and endoderm (GATA6, AFP, and SOX17) …
The number of high-quality cells required for engineering an adult human-sized bioartificial organ is greater than one billion. ...Sp …
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