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Year Number of Results
1984 2
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1989 4
1990 5
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1992 5
1993 18
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1995 29
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1998 32
1999 21
2000 16
2001 24
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2003 24
2004 22
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2006 26
2007 32
2008 34
2009 27
2010 29
2011 44
2012 41
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778 results

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Page 1
Growth hormone releasing hexapeptide-6 (GHRP-6) test in the diagnosis of GH-deficiency.
Pombo M, Leal-Cerro A, Barreiro J, Peñalva A, Peino R, Mallo F, Dieguez C, Casanueva FF. Pombo M, et al. J Pediatr Endocrinol Metab. 1996 Jun;9 Suppl 3:333-8. J Pediatr Endocrinol Metab. 1996. PMID: 8887178 Review.
Although we found that the GH response to GHRP-6 was lower in patients with GHD than in normal children, on an individual basis a considerable degree of overlap was observed between the two groups. In contrast, we found an almost complete blockade of GH response to …
Although we found that the GH response to GHRP-6 was lower in patients with GHD than in normal children, on an individual basi …
Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy via metabolic regulation.
Zhao X, Pan K, Li R, Liu M, Li D, Jia P, Han Z, Han ZC, Guo Z, Li Z, Li Q. Zhao X, et al. J Nanobiotechnology. 2025 Dec 1;24(1):15. doi: 10.1186/s12951-025-03888-9. J Nanobiotechnology. 2025. PMID: 41327290 Free PMC article.
Metabolomic sequencing analysis revealed that spermidine, L-glutamine, and acetyl-CoA, which are involved in amino acid and fatty acid metabolism, were highly enriched in a mouse model of AKI treated with the GHRP-6 hydrogel. Further study revealed that GHRP- …
Metabolomic sequencing analysis revealed that spermidine, L-glutamine, and acetyl-CoA, which are involved in amino acid and fatty acid metab …
[D-Lys3]-GHRP-6 exhibits pro-autophagic effects on skeletal muscle.
Yu AP, Pei XM, Sin TK, Yip SP, Yung BY, Chan LW, Wong CS, Siu PM. Yu AP, et al. Mol Cell Endocrinol. 2015 Feb 5;401:155-64. doi: 10.1016/j.mce.2014.09.031. Epub 2014 Oct 29. Mol Cell Endocrinol. 2015. PMID: 25450862
[D-Lys3]-GHRP-6 reduced the activation of muscle apoptosis induced by doxorubicin. No histological abnormalities were observed in the [D-Lys3]-GHRP-6-treated muscle. ...The [D-Lys3]-GHRP-6-induced activation of autophagy was found to be a …
[D-Lys3]-GHRP-6 reduced the activation of muscle apoptosis induced by doxorubicin. No histological abnormalities were observed …
Growth hormone releasing peptide-6 (GHRP-6) prevents doxorubicin-induced myocardial and extra-myocardial damages by activating prosurvival mechanisms.
Berlanga-Acosta J, Cibrian D, Valiente-Mustelier J, Suárez-Alba J, García-Ojalvo A, Falcón-Cama V, Jiang B, Wang L, Guillén-Nieto G. Berlanga-Acosta J, et al. Front Pharmacol. 2024 May 30;15:1402138. doi: 10.3389/fphar.2024.1402138. eCollection 2024. Front Pharmacol. 2024. PMID: 38873418 Free PMC article.
Experimentally reproduced DCM/HF through Dox administrations has shed light on the pathogenic drivers of cardiotoxicity. Growth hormone (GH) releasing peptide 6 (GHRP-6) is a GH secretagogue with expanding and promising cardioprotective pharmacological proper …
Experimentally reproduced DCM/HF through Dox administrations has shed light on the pathogenic drivers of cardiotoxicity. Growth hormone (GH) …
Evaluation of pituitary GH reserve with GHRP-6.
Popovic V, Micic D, Damjanovic S, Djurovic M, Simic M, Gligorovic M, Dieguez C, Casanueva FF. Popovic V, et al. J Pediatr Endocrinol Metab. 1996 Jun;9 Suppl 3:289-98. J Pediatr Endocrinol Metab. 1996. PMID: 8887173 Review.
In different metabolic states GH response after GHRH is more impaired than after GHRP-6. On the other hand in different neuroendocrine pathologies GH response after GHRP-6 is more impaired than after GHRH. ...
In different metabolic states GH response after GHRH is more impaired than after GHRP-6. On the other hand in different neuroe …
GHRP-6 is able to stimulate cortisol and ACTH release in patients with Cushing's disease: comparison with DDAVP.
Oliveira JH, Vieira JG, Abucham J, Lengyel AM. Oliveira JH, et al. J Endocrinol Invest. 2003 Mar;26(3):230-5. doi: 10.1007/BF03345162. J Endocrinol Invest. 2003. PMID: 12809173 Clinical Trial.
The aim of this study was to evaluate the ACTH and cortisol releasing effects of GHRP-6 in patients with Cushing's disease and to compare them with those obtained with DDAVP administration. ...There was a significant positive correlation between peak cortisol values …
The aim of this study was to evaluate the ACTH and cortisol releasing effects of GHRP-6 in patients with Cushing's disease and …
GHRP-6 induces CREB phosphorylation and growth hormone secretion via a protein kinase Csigma-dependent pathway in GH3 cells.
Tian C, Ye F, Xu T, Wang S, Wang X, Wang H, Wan F, Lei T. Tian C, et al. J Huazhong Univ Sci Technolog Med Sci. 2010 Apr;30(2):183-7. doi: 10.1007/s11596-010-0210-5. Epub 2010 Apr 21. J Huazhong Univ Sci Technolog Med Sci. 2010. PMID: 20407870
GH3 cells were cultured and subjected to different treatments as follows: GHRP-6, GHRP-6 plus GHRH, phorbol ester (PMA), an activator of PKC, alone or in combination with GHRP-6, Go6983, a general inhibitor of PKCs, in the presence or abs …
GH3 cells were cultured and subjected to different treatments as follows: GHRP-6, GHRP-6 plus GHRH, phorbol este …
N-aminoimidazolidin-2-one peptidomimetics.
Doan ND, Hopewell R, Lubell WD. Doan ND, et al. Org Lett. 2014 Apr 18;16(8):2232-5. doi: 10.1021/ol500739k. Epub 2014 Apr 4. Org Lett. 2014. PMID: 24697286
The syntheses and isolation of 25 Aid peptides, including eight GHRP-6 analogues, are reported to demonstrate the utility of this method for controlling conformation....
The syntheses and isolation of 25 Aid peptides, including eight GHRP-6 analogues, are reported to demonstrate the utility of t …
Ghrelin antagonist D-Lys3-GHRP-6 counteract ghrelin effects in bovine cumulus-oocytes complexes matured in vitro.
Carranza-Martín AC, Nikoloff N, Anchordoquy JP, Anchordoquy JM, Relling AE, Furnus CC. Carranza-Martín AC, et al. Reprod Domest Anim. 2021 Sep;56(9):1235-1242. doi: 10.1111/rda.13982. Epub 2021 Jul 14. Reprod Domest Anim. 2021. PMID: 34173284
The aim of this study was to evaluate the effect of ghrelin antagonist D-Lys3-GHRP-6 (GA) as a potential agent that prevents ghrelin effects during bovine oocyte maturation on progesterone production, cumulus cell (CC) viability, CC DNA damage and embryo development …
The aim of this study was to evaluate the effect of ghrelin antagonist D-Lys3-GHRP-6 (GA) as a potential agent that prevents g …
778 results