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Year Number of Results
1994 1
1996 1
1997 1
2000 1
2001 2
2002 1
2007 1
2020 0
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Page 1
Synthesis and evaluation of GGPP geometric isomers: divergent substrate specificities of FTase and GGTase I.
Zahn TJ, Whitney J, Weinbaum C, Gibbs RA. Zahn TJ, et al. Bioorg Med Chem Lett. 2001 Jun 18;11(12):1605-8. doi: 10.1016/s0960-894x(01)00292-x. Bioorg Med Chem Lett. 2001. PMID: 11412990
Lysine(164)alpha of protein farnesyltransferase is important for both CaaX substrate binding and catalysis.
Hightower KE, De S, Weinbaum C, Spence RA, Casey PJ. Hightower KE, et al. Biochem J. 2001 Dec 15;360(Pt 3):625-31. doi: 10.1042/0264-6021:3600625. Biochem J. 2001. PMID: 11736652 Free PMC article.
GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer.
Sjogren AK, Andersson KM, Liu M, Cutts BA, Karlsson C, Wahlstrom AM, Dalin M, Weinbaum C, Casey PJ, Tarkowski A, Swolin B, Young SG, Bergo MO. Sjogren AK, et al. J Clin Invest. 2007 May;117(5):1294-304. doi: 10.1172/JCI30868. J Clin Invest. 2007. PMID: 17476360 Free PMC article.
Stereospecificity and kinetic mechanism of human prenylcysteine lyase, an unusual thioether oxidase.
Digits JA, Pyun HJ, Coates RM, Casey PJ. Digits JA, et al. J Biol Chem. 2002 Oct 25;277(43):41086-93. doi: 10.1074/jbc.M208069200. Epub 2002 Aug 16. J Biol Chem. 2002. PMID: 12186880 Free article.
Farnesyltransferase inhibitors alter the prenylation and growth-stimulating function of RhoB.
Lebowitz PF, Casey PJ, Prendergast GC, Thissen JA. Lebowitz PF, et al. J Biol Chem. 1997 Jun 20;272(25):15591-4. doi: 10.1074/jbc.272.25.15591. J Biol Chem. 1997. PMID: 9188444 Free article.
Properties and kinetic mechanism of recombinant mammalian protein geranylgeranyltransferase type I.
Zhang FL, Moomaw JF, Casey PJ. Zhang FL, et al. J Biol Chem. 1994 Sep 23;269(38):23465-70. J Biol Chem. 1994. PMID: 8089111 Free article.
Grignard-mediated synthesis and preliminary biological evaluation of novel 3-substituted farnesyl diphosphate analogues.
Zahn TJ, Weinbaum C, Gibbs RA. Zahn TJ, et al. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1763-6. doi: 10.1016/s0960-894x(00)00337-1. Bioorg Med Chem Lett. 2000. PMID: 10937743
Kinetics of protein farnesyltransferase: sigmoidal vs hyperbolic behavior as a function of assay conditions.
Thissen JA, Casey PJ. Thissen JA, et al. Anal Biochem. 1996 Dec 1;243(1):80-5. doi: 10.1006/abio.1996.0484. Anal Biochem. 1996. PMID: 8954528