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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 2
1991 9
1992 5
1993 6
1994 4
1995 1
1996 1
1999 1
2000 2
2001 3
2002 1
2003 1
2004 1
2009 2
2020 0
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39 results
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Page 1
Immunophilin-ligand complexes as probes of intracellular signaling pathways.
Schreiber SL, Liu J, Albers MW, Karmacharya R, Koh E, Martin PK, Rosen MK, Standaert RF, Wandless TJ. Schreiber SL, et al. Transplant Proc. 1991 Dec;23(6):2839-44. Transplant Proc. 1991. PMID: 1721293 Review. No abstract available.
Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog.
Peng LF, Stanton BZ, Maloof N, Wang X, Schreiber SL. Peng LF, et al. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6319-25. doi: 10.1016/j.bmcl.2009.09.089. Epub 2009 Sep 25. Bioorg Med Chem Lett. 2009. PMID: 19819139 Free PMC article.
Probing immunosuppressant action with a nonnatural immunophilin ligand.
Bierer BE, Somers PK, Wandless TJ, Burakoff SJ, Schreiber SL. Bierer BE, et al. Science. 1990 Oct 26;250(4980):556-9. doi: 10.1126/science.1700475. Science. 1990. PMID: 1700475
Rpd3p relocation mediates a transcriptional response to rapamycin in yeast.
Humphrey EL, Shamji AF, Bernstein BE, Schreiber SL. Humphrey EL, et al. Chem Biol. 2004 Mar;11(3):295-9. doi: 10.1016/j.chembiol.2004.03.001. Chem Biol. 2004. PMID: 15123258
A rapamycin-selective 25-kDa immunophilin.
Galat A, Lane WS, Standaert RF, Schreiber SL. Galat A, et al. Biochemistry. 1992 Mar 3;31(8):2427-34. doi: 10.1021/bi00123a031. Biochemistry. 1992. PMID: 1371698
Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.
Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J. Van Duyne GD, et al. Science. 1991 May 10;252(5007):839-42. doi: 10.1126/science.1709302. Science. 1991. PMID: 1709302
A small molecule that binds Hedgehog and blocks its signaling in human cells.
Stanton BZ, Peng LF, Maloof N, Nakai K, Wang X, Duffner JL, Taveras KM, Hyman JM, Lee SW, Koehler AN, Chen JK, Fox JL, Mandinova A, Schreiber SL. Stanton BZ, et al. Nat Chem Biol. 2009 Mar;5(3):154-6. doi: 10.1038/nchembio.142. Epub 2009 Jan 18. Nat Chem Biol. 2009. PMID: 19151731 Free PMC article.
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