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1997 7
1998 2
2001 3
2021 0
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Page 1
Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond.
Artursson P, Borchardt RT. Artursson P, et al. Pharm Res. 1997 Dec;14(12):1655-8. doi: 10.1023/a:1012155124489. Pharm Res. 1997. PMID: 9453050 Review. No abstract available.
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells.
Gao J, Murase O, Schowen RL, Aubé J, Borchardt RT. Gao J, et al. Pharm Res. 2001 Feb;18(2):171-6. doi: 10.1023/a:1011076217118. Pharm Res. 2001. PMID: 11405287
Effect of stereochemistry on the transport of Aca-linked beta-turn peptidomimetics across a human intestinal cell line.
Tamura K, Agrios KA, Vander Velde D, Aubé J, Borchardt RT. Tamura K, et al. Bioorg Med Chem. 1997 Sep;5(9):1859-66. doi: 10.1016/s0968-0896(97)00115-6. Bioorg Med Chem. 1997. PMID: 9354242
Structure-affinity relationships of Val-Val and Val-Val-Val stereoisomers with the apical oligopeptide transporter in human intestinal Caco-2 cells.
Li J, Tamura K, Lee CP, Smith PL, Borchardt RT, Hidalgo IJ. Li J, et al. J Drug Target. 1998;5(5):317-27. doi: 10.3109/10611869808997860. J Drug Target. 1998. PMID: 9771614
Effect of size and charge on the passive diffusion of peptides across Caco-2 cell monolayers via the paracellular pathway.
Pauletti GM, Okumu FW, Borchardt RT. Pauletti GM, et al. Pharm Res. 1997 Feb;14(2):164-8. doi: 10.1023/a:1012040425146. Pharm Res. 1997. PMID: 9090703
Transport characteristics of peptidomimetics. Effect of the pyrrolinone bioisostere on transport across Caco-2 cell monolayers.
Sudoh M, Pauletti GM, Yao W, Moser W, Yokoyama A, Pasternak A, Sprengeler PA, Smith AB 3rd, Hirschmann R, Borchardt RT. Sudoh M, et al. Pharm Res. 1998 May;15(5):719-25. doi: 10.1023/a:1011966918959. Pharm Res. 1998. PMID: 9619780
The effect of beta-turn structure on the permeation of peptides across monolayers of bovine brain microvessel endothelial cells.
Sorensen M, Steenberg B, Knipp GT, Wang W, Steffansen B, Frokjaer S, Borchardt RT. Sorensen M, et al. Pharm Res. 1997 Oct;14(10):1341-8. doi: 10.1023/a:1012104301773. Pharm Res. 1997. PMID: 9358545
Transport characteristics of peptides and peptidomimetics: I. N-methylated peptides as substrates for the oligopeptide transporter and P-glycoprotein in the intestinal mucosa.
Gao J, Sudoh M, Aubé J, Borchardt RT. Gao J, et al. J Pept Res. 2001 Apr;57(4):316-29. doi: 10.1046/j.1397-002x.2001.00000.x. J Pept Res. 2001. PMID: 11328489
Paracellular diffusion in Caco-2 cell monolayers: effect of perturbation on the transport of hydrophilic compounds that vary in charge and size.
Knipp GT, Ho NF, Barsuhn CL, Borchardt RT. Knipp GT, et al. J Pharm Sci. 1997 Oct;86(10):1105-10. doi: 10.1021/js9700309. J Pharm Sci. 1997. PMID: 9344165
The effect of beta-turn structure on the passive diffusion of peptides across Caco-2 cell monolayers.
Knipp GT, Vander Velde DG, Siahaan TJ, Borchardt RT. Knipp GT, et al. Pharm Res. 1997 Oct;14(10):1332-40. doi: 10.1023/a:1012152117703. Pharm Res. 1997. PMID: 9358544
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