GM085585/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2009	5
2010	6
2011	3
2012	1
2014	3
2024	0

1

The c-MYC NHE III(1): function and regulation.

González V, Hurley LH. González V, et al. Annu Rev Pharmacol Toxicol. 2010;50:111-29. doi: 10.1146/annurev.pharmtox.48.113006.094649. Annu Rev Pharmacol Toxicol. 2010. PMID: 19922264 Review.

2

DNA acting like RNA.

Brown RV, Hurley LH. Brown RV, et al. Biochem Soc Trans. 2011 Apr;39(2):635-40. doi: 10.1042/BST0390635. Biochem Soc Trans. 2011. PMID: 21428953 Free PMC article. Review.

3

The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics.

Brooks TA, Hurley LH. Brooks TA, et al. Nat Rev Cancer. 2009 Dec;9(12):849-61. doi: 10.1038/nrc2733. Epub 2009 Nov 12. Nat Rev Cancer. 2009. PMID: 19907434 Review.

4

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

Balasubramanian S, Hurley LH, Neidle S. Balasubramanian S, et al. Nat Rev Drug Discov. 2011 Apr;10(4):261-75. doi: 10.1038/nrd3428. Nat Rev Drug Discov. 2011. PMID: 21455236 Free PMC article. Review.

5

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

Brooks TA, Kendrick S, Hurley L. Brooks TA, et al. FEBS J. 2010 Sep;277(17):3459-69. doi: 10.1111/j.1742-4658.2010.07759.x. Epub 2010 Jul 29. FEBS J. 2010. PMID: 20670278 Free PMC article. Review.

6

Targeting MYC Expression through G-Quadruplexes.

Brooks TA, Hurley LH. Brooks TA, et al. Genes Cancer. 2010 Jun;1(6):641-649. doi: 10.1177/1947601910377493. Genes Cancer. 2010. PMID: 21113409 Free PMC article.

7

Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex.

Brown RV, Danford FL, Gokhale V, Hurley LH, Brooks TA. Brown RV, et al. J Biol Chem. 2011 Nov 25;286(47):41018-27. doi: 10.1074/jbc.M111.274720. Epub 2011 Sep 28. J Biol Chem. 2011. PMID: 21956115 Free PMC article.

8

Molecular population dynamics of DNA structures in a bcl-2 promoter sequence is regulated by small molecules and the transcription factor hnRNP LL.

Cui Y, Koirala D, Kang H, Dhakal S, Yangyuoru P, Hurley LH, Mao H. Cui Y, et al. Nucleic Acids Res. 2014 May;42(9):5755-64. doi: 10.1093/nar/gku185. Epub 2014 Mar 7. Nucleic Acids Res. 2014. PMID: 24609386 Free PMC article.

9

The role of G-quadruplex/i-motif secondary structures as cis-acting regulatory elements.

Kendrick S, Hurley LH. Kendrick S, et al. Pure Appl Chem. 2010 Jan 1;82(8):1609-1621. doi: 10.1351/PAC-CON-09-09-29. Pure Appl Chem. 2010. PMID: 21796223 Free PMC article.

10

The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression.

Sun D, Hurley LH. Sun D, et al. J Med Chem. 2009 May 14;52(9):2863-74. doi: 10.1021/jm900055s. J Med Chem. 2009. PMID: 19385599 Free PMC article.

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