GM43511/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
1994	1
1995	1
1997	1
1998	2
2000	3
2001	2
2002	1
2003	3
2006	1
2021	0

1

Bioactivation of N-substituted N'-(4-imidazole-ethyl)thioureas by human FMO1 and FMO3.

Onderwater RC, Rettie AE, Commandeur JN, Vermeulen NP. Onderwater RC, et al. Xenobiotica. 2006 Jul;36(7):645-57. doi: 10.1080/00498250500354329. Xenobiotica. 2006. PMID: 16864509

2

Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group.

Cheesman MJ, Baer BR, Zheng YM, Gillam EM, Rettie AE. Cheesman MJ, et al. Arch Biochem Biophys. 2003 Aug 1;416(1):17-24. doi: 10.1016/s0003-9861(03)00278-9. Arch Biochem Biophys. 2003. PMID: 12859977

3

Can caffeine metabolism be used as an in-vivo probe for human flavin-containing monooxygenase activity?

Rettie AE, Lang DH. Rettie AE, et al. Pharmacogenetics. 2000 Apr;10(3):275-7. doi: 10.1097/00008571-200004000-00010. Pharmacogenetics. 2000. PMID: 10803685 No abstract available.

4

Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression.

Koukouritaki SB, Simpson P, Yeung CK, Rettie AE, Hines RN. Koukouritaki SB, et al. Pediatr Res. 2002 Feb;51(2):236-43. doi: 10.1203/00006450-200202000-00018. Pediatr Res. 2002. PMID: 11809920

5

Purification and characterization of hexahistidine-tagged cyclohexanone monooxygenase expressed in Saccharomyces cerevisiae and Escherichia coli.

Cheesman MJ, Kneller MB, Kelly EJ, Thompson SJ, Yeung CK, Eaton DL, Rettie AE. Cheesman MJ, et al. Protein Expr Purif. 2001 Feb;21(1):81-6. doi: 10.1006/prep.2000.1340. Protein Expr Purif. 2001. PMID: 11162390

6

Baculovirus-mediated expression and purification of human FMO3: catalytic, immunochemical, and structural characterization.

Haining RL, Hunter AP, Sadeque AJ, Philpot RM, Rettie AE. Haining RL, et al. Drug Metab Dispos. 1997 Jul;25(7):790-7. Drug Metab Dispos. 1997. PMID: 9224773

7

Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3.

Lang DH, Yeung CK, Peter RM, Ibarra C, Gasser R, Itagaki K, Philpot RM, Rettie AE. Lang DH, et al. Biochem Pharmacol. 1998 Oct 15;56(8):1005-12. doi: 10.1016/s0006-2952(98)00218-4. Biochem Pharmacol. 1998. PMID: 9776311

8

Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid.

Guan X, Fisher MB, Lang DH, Zheng YM, Koop DR, Rettie AE. Guan X, et al. Chem Biol Interact. 1998 Mar 12;110(1-2):103-21. doi: 10.1016/s0009-2797(97)00145-2. Chem Biol Interact. 1998. PMID: 9566728

9

Prochiral sulfoxidation as a probe for multiple forms of the microsomal flavin-containing monooxygenase: studies with rabbit FMO1, FMO2, FMO3, and FMO5 expressed in Escherichia coli.

Rettie AE, Lawton MP, Sadeque AJ, Meier GP, Philpot RM. Rettie AE, et al. Arch Biochem Biophys. 1994 Jun;311(2):369-77. doi: 10.1006/abbi.1994.1250. Arch Biochem Biophys. 1994. PMID: 8203899

10

In vitro evaluation of potential in vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms.

Lang DH, Rettie AE. Lang DH, et al. Br J Clin Pharmacol. 2000 Oct;50(4):311-4. doi: 10.1046/j.1365-2125.2000.00265.x. Br J Clin Pharmacol. 2000. PMID: 11012553 Free PMC article.

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