GM60620/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

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Year	Number of Results
2002	1
2006	1
2007	1
2008	2
2009	2
2010	1
2022	0

Page 1

Establishing a mechanistic basis for the large kinetic steps of the NS3 helicase.

Serebrov V, Beran RK, Pyle AM. Serebrov V, et al. J Biol Chem. 2009 Jan 23;284(4):2512-21. doi: 10.1074/jbc.M805460200. Epub 2008 Nov 14. J Biol Chem. 2009. PMID: 19010782 Free PMC article.

Hepatitis C viral NS3-4A protease activity is enhanced by the NS3 helicase.

Beran RK, Pyle AM. Beran RK, et al. J Biol Chem. 2008 Oct 31;283(44):29929-37. doi: 10.1074/jbc.M804065200. Epub 2008 Aug 22. J Biol Chem. 2008. PMID: 18723512 Free PMC article.

The NS4A protein of hepatitis C virus promotes RNA-coupled ATP hydrolysis by the NS3 helicase.

Beran RK, Lindenbach BD, Pyle AM. Beran RK, et al. J Virol. 2009 Apr;83(7):3268-75. doi: 10.1128/JVI.01849-08. Epub 2009 Jan 19. J Virol. 2009. PMID: 19153239 Free PMC article.

The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate.

Beran RK, Serebrov V, Pyle AM. Beran RK, et al. J Biol Chem. 2007 Nov 30;282(48):34913-20. doi: 10.1074/jbc.M707165200. Epub 2007 Oct 5. J Biol Chem. 2007. PMID: 17921146 Free article.

The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding.

Pang PS, Jankowsky E, Planet PJ, Pyle AM. Pang PS, et al. EMBO J. 2002 Mar 1;21(5):1168-76. doi: 10.1093/emboj/21.5.1168. EMBO J. 2002. PMID: 11867545 Free PMC article.

Robust translocation along a molecular monorail: the NS3 helicase from hepatitis C virus traverses unusually large disruptions in its track.

Beran RK, Bruno MM, Bowers HA, Jankowsky E, Pyle AM. Beran RK, et al. J Mol Biol. 2006 May 12;358(4):974-82. doi: 10.1016/j.jmb.2006.02.078. Epub 2006 Mar 20. J Mol Biol. 2006. PMID: 16569413

The NPH-II helicase displays efficient DNA x RNA helicase activity and a pronounced purine sequence bias.

Taylor SD, Solem A, Kawaoka J, Pyle AM. Taylor SD, et al. J Biol Chem. 2010 Apr 9;285(15):11692-703. doi: 10.1074/jbc.M109.088559. Epub 2010 Jan 28. J Biol Chem. 2010. PMID: 20110368 Free PMC article.

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