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Year Number of Results
1980 1
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1983 5
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1988 20
1989 33
1990 69
1991 115
1992 176
1993 181
1994 182
1995 217
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1997 266
1998 316
1999 329
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2001 412
2002 398
2003 469
2004 508
2005 525
2006 607
2007 562
2008 627
2009 594
2010 594
2011 670
2012 726
2013 753
2014 761
2015 734
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2018 691
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2024 638
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2026 1

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16,403 results

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Page 1
The role of GTPase-activating protein ARHGAP26 in human cancers.
Zhang L, Zhou A, Zhu S, Min L, Liu S, Li P, Zhang S. Zhang L, et al. Mol Cell Biochem. 2022 Jan;477(1):319-326. doi: 10.1007/s11010-021-04274-3. Epub 2021 Oct 30. Mol Cell Biochem. 2022. PMID: 34716859 Free PMC article. Review.
Rho GTPases are molecular switches that play an important role in regulating the behavior of a variety of tumor cells. RhoA GTPase-activating protein 26 (ARHGAP26) is a GTPase-activating protein and inhibits the activity of Rho GTPases by …
Rho GTPases are molecular switches that play an important role in regulating the behavior of a variety of tumor cells. RhoA GTPase- …
Rho GTPase Activating Protein 9 (ARHGAP9) in Human Cancers.
Song W, Chen J, Li S, Li D, Zhang Y, Zhou H, Yu W, He B, Zhang W, Li L. Song W, et al. Recent Pat Anticancer Drug Discov. 2022;17(1):55-65. doi: 10.2174/1574892816666210806155754. Recent Pat Anticancer Drug Discov. 2022. PMID: 34365932 Review.
OBJECTIVES: This study aimed to summarize the role of the Rho GTPase activating protein 9 (ARHGAP9) gene in tumorigenesis and development to discover therapeutic targets for cancer in the future. ...
OBJECTIVES: This study aimed to summarize the role of the Rho GTPase activating protein 9 (ARHGAP9) gene in tumorigenes …
The Ras/Rap GTPase activating protein RASA3: from gene structure to in vivo functions.
Schurmans S, Polizzi S, Scoumanne A, Sayyed S, Molina-Ortiz P. Schurmans S, et al. Adv Biol Regul. 2015 Jan;57:153-61. doi: 10.1016/j.jbior.2014.09.006. Epub 2014 Sep 28. Adv Biol Regul. 2015. PMID: 25294679 Review.
RASA3 (or GTPase Activating Protein III, R-Ras GTPase-activating protein, GAP1(IP4BP)) is a GTPase activating protein of the GAP1 subfamily which targets Ras and Rap1. ...
RASA3 (or GTPase Activating Protein III, R-Ras GTPase-activating protein, GAP1(IP4BP)) is a GTP
Rac GTPase-Activating Protein 1 (RACGAP1) as an Oncogenic Enhancer in Esophageal Carcinoma.
Yin C, Toiyama Y, Okugawa Y, Shigemori T, Yamamoto A, Ide S, Kitajima T, Fujikawa H, Yasuda H, Okita Y, Hiro J, Yoshiyama S, Ohi M, Araki T, Yao L, Kusunoki M. Yin C, et al. Oncology. 2019;97(3):155-163. doi: 10.1159/000500592. Epub 2019 Jun 19. Oncology. 2019. PMID: 31216559
PURPOSE: Rac GTPase-activating protein 1 (RACGAP1) is associated with cell proliferation, and there is much evidence of its oncogenic role. ...
PURPOSE: Rac GTPase-activating protein 1 (RACGAP1) is associated with cell proliferation, and there is much evidence of …
GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins.
Ross EM, Wilkie TM. Ross EM, et al. Annu Rev Biochem. 2000;69:795-827. doi: 10.1146/annurev.biochem.69.1.795. Annu Rev Biochem. 2000. PMID: 10966476 Review.
GTPase-activating proteins (GAPs) regulate heterotrimeric G proteins by increasing the rates at which their subunits hydrolyze bound GTP and thus return to the inactive state. G protein GAPs act allosterically on G subunits, in contrast to GAPs
GTPase-activating proteins (GAPs) regulate heterotrimeric G proteins by increasing the rates at which their subu
Ras-GTPase activating protein (GAP): a putative effector for Ras.
Tocque B, Delumeau I, Parker F, Maurier F, Multon MC, Schweighoffer F. Tocque B, et al. Cell Signal. 1997 Feb;9(2):153-8. doi: 10.1016/s0898-6568(96)00135-0. Cell Signal. 1997. PMID: 9113414 Review.
One attractive candidate for a Ras effector protein, other than the Raf kinases, is Ras-GAP. Indeed, recent literature suggests that besides the Raf/MAP kinase cascade, additional pathways must be stimulated to elicit a full biological response to Ras. ...The newly found G …
One attractive candidate for a Ras effector protein, other than the Raf kinases, is Ras-GAP. Indeed, recent literature suggests that …
The Cdc42 GTPase-activating protein Rga6 promotes the cortical localization of septin.
Zheng S, Zheng B, Liu Z, Ma X, Liu X, Yao X, Wei W, Fu C. Zheng S, et al. J Cell Sci. 2022 Feb 15;135(4):jcs259228. doi: 10.1242/jcs.259228. Epub 2022 Feb 16. J Cell Sci. 2022. PMID: 35048989
Septins are a family of filament-forming GTP-binding proteins that regulate fundamental cellular activities, such as cytokinesis and cell polarity. ...However, little is known about the mechanism that governs the recruitment and localization of the septin complex to the ce …
Septins are a family of filament-forming GTP-binding proteins that regulate fundamental cellular activities, such as cytokinesis and …
p120-Ras GTPase activating protein (RasGAP): a multi-interacting protein in downstream signaling.
Pamonsinlapatham P, Hadj-Slimane R, Lepelletier Y, Allain B, Toccafondi M, Garbay C, Raynaud F. Pamonsinlapatham P, et al. Biochimie. 2009 Mar;91(3):320-8. doi: 10.1016/j.biochi.2008.10.010. Epub 2008 Oct 30. Biochimie. 2009. PMID: 19022332 Review.
p120-RasGAP (Ras GTPase activating protein) plays a key role in the regulation of Ras-GTP bound by promoting GTP hydrolysis via its C-terminal catalytic domain. ...The p120-RasGAP domain participates in protein-protein interactions with Akt, Aur …
p120-RasGAP (Ras GTPase activating protein) plays a key role in the regulation of Ras-GTP bound by promoting GTP hydrol …
Ablating the Rab-GTPase activating protein TBC1D1 predisposes rats to high-fat diet-induced cardiomyopathy.
Barbeau PA, Houad JM, Huber JS, Paglialunga S, Snook LA, Herbst EAF, Dennis KMJH, Simpson JA, Holloway GP. Barbeau PA, et al. J Physiol. 2020 Feb;598(4):683-697. doi: 10.1113/JP279042. Epub 2020 Feb 4. J Physiol. 2020. PMID: 31845331 Free article.
TBC1D1 ablation increased plasma membrane fatty acid binding protein content and myocardial palmitate oxidation. Following high-fat feeding, TBC1D1 ablation dramatically increased fibrosis and induced end-diastolic dysfunction in both male and female rats in the absence of …
TBC1D1 ablation increased plasma membrane fatty acid binding protein content and myocardial palmitate oxidation. Following high-fat f …
16,403 results
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