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Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases.
Gabathuler R. Gabathuler R. Neurobiol Dis. 2010 Jan;37(1):48-57. doi: 10.1016/j.nbd.2009.07.028. Epub 2009 Aug 5. Neurobiol Dis. 2010. PMID: 19664710 Review.
Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2.
Régina A, Demeule M, Ché C, Lavallée I, Poirier J, Gabathuler R, Béliveau R, Castaigne JP. Régina A, et al. Among authors: gabathuler r. Br J Pharmacol. 2008 Sep;155(2):185-97. doi: 10.1038/bjp.2008.260. Epub 2008 Jun 23. Br J Pharmacol. 2008. PMID: 18574456 Free PMC article.
[New protein vectors for physiological transfer of therapeutic agents to the central nervous system].
Gabathuler R. Gabathuler R. Biol Aujourdhui. 2012;206(3):191-203. doi: 10.1051/jbio/2012018. Epub 2012 Nov 22. Biol Aujourdhui. 2012. PMID: 23171842 Review. French.
Development of new peptide vectors for the transport of therapeutic across the blood-brain barrier.
Gabathuler R. Gabathuler R. Ther Deliv. 2010 Oct;1(4):571-86. doi: 10.4155/tde.10.35. Ther Deliv. 2010. PMID: 22833968 Review.
Blood-brain barrier transport of drugs for the treatment of brain diseases.
Gabathuler R. Gabathuler R. CNS Neurol Disord Drug Targets. 2009 Jun;8(3):195-204. doi: 10.2174/187152709788680652. CNS Neurol Disord Drug Targets. 2009. PMID: 19601817 Review.
Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2.
Demeule M, Currie JC, Bertrand Y, Ché C, Nguyen T, Régina A, Gabathuler R, Castaigne JP, Béliveau R. Demeule M, et al. Among authors: gabathuler r. J Neurochem. 2008 Aug;106(4):1534-44. doi: 10.1111/j.1471-4159.2008.05492.x. Epub 2008 May 19. J Neurochem. 2008. PMID: 18489712 Free article.
A unique carrier for delivery of therapeutic compounds beyond the blood-brain barrier.
Karkan D, Pfeifer C, Vitalis TZ, Arthur G, Ujiie M, Chen Q, Tsai S, Koliatis G, Gabathuler R, Jefferies WA. Karkan D, et al. Among authors: gabathuler r. PLoS One. 2008 Jun 25;3(6):e2469. doi: 10.1371/journal.pone.0002469. PLoS One. 2008. PMID: 18575595 Free PMC article.
Transport characteristics of a novel peptide platform for CNS therapeutics.
Bertrand Y, Currie JC, Demeule M, Régina A, Ché C, Abulrob A, Fatehi D, Sartelet H, Gabathuler R, Castaigne JP, Stanimirovic D, Béliveau R. Bertrand Y, et al. Among authors: gabathuler r. J Cell Mol Med. 2010 Dec;14(12):2827-39. doi: 10.1111/j.1582-4934.2009.00930.x. J Cell Mol Med. 2010. PMID: 19818094 Free PMC article.
Identification and design of peptides as a new drug delivery system for the brain.
Demeule M, Régina A, Ché C, Poirier J, Nguyen T, Gabathuler R, Castaigne JP, Béliveau R. Demeule M, et al. Among authors: gabathuler r. J Pharmacol Exp Ther. 2008 Mar;324(3):1064-72. doi: 10.1124/jpet.107.131318. Epub 2007 Dec 21. J Pharmacol Exp Ther. 2008. PMID: 18156463
Identification of a novel route of iron transcytosis across the mammalian blood-brain barrier.
Moroo I, Ujiie M, Walker BL, Tiong JW, Vitalis TZ, Karkan D, Gabathuler R, Moise AR, Jefferies WA. Moroo I, et al. Among authors: gabathuler r. Microcirculation. 2003 Dec;10(6):457-62. doi: 10.1038/sj.mn.7800213. Microcirculation. 2003. PMID: 14745458
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