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Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.
Kuo YM, Li Z, Jiao Y, Gaborit N, Pani AK, Orrison BM, Bruneau BG, Giasson BI, Smeyne RJ, Gershon MD, Nussbaum RL. Kuo YM, et al. Among authors: gaborit n. Hum Mol Genet. 2010 May 1;19(9):1633-50. doi: 10.1093/hmg/ddq038. Epub 2010 Jan 27. Hum Mol Genet. 2010. PMID: 20106867 Free PMC article.
Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network.
Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olguín P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, Hui CC, Bruneau BG, Backx PH. Zhang SS, et al. Among authors: gaborit n. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13576-81. doi: 10.1073/pnas.1106911108. Epub 2011 Aug 8. Proc Natl Acad Sci U S A. 2011. PMID: 21825130 Free PMC article.
Human model of IRX5 mutations reveals key role for this transcription factor in ventricular conduction.
Al Sayed ZR, Canac R, Cimarosti B, Bonnard C, Gourraud JB, Hamamy H, Kayserili H, Girardeau A, Jouni M, Jacob N, Gaignerie A, Chariau C, David L, Forest V, Marionneau C, Charpentier F, Loussouarn G, Lamirault G, Reversade B, Zibara K, Lemarchand P, Gaborit N. Al Sayed ZR, et al. Among authors: gaborit n. Cardiovasc Res. 2021 Jul 27;117(9):2092-2107. doi: 10.1093/cvr/cvaa259. Cardiovasc Res. 2021. PMID: 32898233 Free article.
Generation of three human induced pluripotent stem cell lines with IRX5 knockout and knockin genetic editions using CRISPR-Cas9 system.
Canac R, Caillaud A, Cimarosti B, Girardeau A, Hamamy H, Reversade B, Bonnard C, Al Sayed ZR, David L, Poschmann J, Lemarchand P, Lamirault G, Gaborit N. Canac R, et al. Among authors: gaborit n. Stem Cell Res. 2022 Jan;58:102627. doi: 10.1016/j.scr.2021.102627. Epub 2021 Dec 13. Stem Cell Res. 2022. PMID: 34929443 Free article.
Deciphering Transcriptional Networks during Human Cardiac Development.
Canac R, Cimarosti B, Girardeau A, Forest V, Olchesqui P, Poschmann J, Redon R, Lemarchand P, Gaborit N, Lamirault G. Canac R, et al. Among authors: gaborit n. Cells. 2022 Dec 3;11(23):3915. doi: 10.3390/cells11233915. Cells. 2022. PMID: 36497174 Free PMC article.
53 results