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Differential polymerase activity in avian and mammalian cells determines host range of influenza virus.
Gabriel G, Abram M, Keiner B, Wagner R, Klenk HD, Stech J. Gabriel G, et al. J Virol. 2007 Sep;81(17):9601-4. doi: 10.1128/JVI.00666-07. Epub 2007 Jun 13. J Virol. 2007. PMID: 17567688 Free PMC article.
As recently shown, mutations in the polymerase genes causing increased polymerase activity in mammalian cells are responsible for the adaptation of the highly pathogenic avian influenza virus SC35 (H7N7) to mice (G. Gabriel et al., Proc. Natl. Acad. Sci. USA 102:185 …
As recently shown, mutations in the polymerase genes causing increased polymerase activity in mammalian cells are responsible for the adapta …
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