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Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A.
Sheridan JT, Worthington EN, Yu K, Gabriel SE, Hartzell HC, Tarran R. Sheridan JT, et al. J Biol Chem. 2011 Jan 14;286(2):1381-8. doi: 10.1074/jbc.M110.174847. Epub 2010 Nov 5. J Biol Chem. 2011. PMID: 21056985 Free PMC article.
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium.
Zhang L, Button B, Gabriel SE, Burkett S, Yan Y, Skiadopoulos MH, Dang YL, Vogel LN, McKay T, Mengos A, Boucher RC, Collins PL, Pickles RJ. Zhang L, et al. PLoS Biol. 2009 Jul;7(7):e1000155. doi: 10.1371/journal.pbio.1000155. Epub 2009 Jul 21. PLoS Biol. 2009. PMID: 19621064 Free PMC article.
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways.
Rock JR, O'Neal WK, Gabriel SE, Randell SH, Harfe BD, Boucher RC, Grubb BR. Rock JR, et al. J Biol Chem. 2009 May 29;284(22):14875-80. doi: 10.1074/jbc.C109.000869. Epub 2009 Apr 10. J Biol Chem. 2009. PMID: 19363029 Free PMC article.
SERCA pump inhibitors do not correct biosynthetic arrest of deltaF508 CFTR in cystic fibrosis.
Grubb BR, Gabriel SE, Mengos A, Gentzsch M, Randell SH, Van Heeckeren AM, Knowles MR, Drumm ML, Riordan JR, Boucher RC. Grubb BR, et al. Am J Respir Cell Mol Biol. 2006 Mar;34(3):355-63. doi: 10.1165/rcmb.2005-0286OC. Epub 2005 Nov 11. Am J Respir Cell Mol Biol. 2006. PMID: 16284361 Free PMC article.
Regulation of the epithelial sodium channel by serine proteases in human airways.
Donaldson SH, Hirsh A, Li DC, Holloway G, Chao J, Boucher RC, Gabriel SE. Donaldson SH, et al. J Biol Chem. 2002 Mar 8;277(10):8338-45. doi: 10.1074/jbc.M105044200. Epub 2001 Dec 26. J Biol Chem. 2002. PMID: 11756432
Regulation of murine airway surface liquid volume by CFTR and Ca2+-activated Cl- conductances.
Tarran R, Loewen ME, Paradiso AM, Olsen JC, Gray MA, Argent BE, Boucher RC, Gabriel SE. Tarran R, et al. J Gen Physiol. 2002 Sep;120(3):407-18. doi: 10.1085/jgp.20028599. J Gen Physiol. 2002. PMID: 12198094 Free PMC article.
INO-4995 therapeutic efficacy is enhanced with repeat dosing in cystic fibrosis knockout mice and human epithelia.
Traynor-Kaplan AE, Moody M, Nur M, Gabriel S, Majerus PW, Drumm ML, Langton-Webster B. Traynor-Kaplan AE, et al. Am J Respir Cell Mol Biol. 2010 Jan;42(1):105-12. doi: 10.1165/rcmb.2008-0380OC. Epub 2009 Apr 3. Am J Respir Cell Mol Biol. 2010. PMID: 19346319 Free PMC article.
CFTR-like chloride channels in non-ciliated bronchiolar epithelial (Clara) cells.
Chinet TC, Gabriel SE, Penland CM, Sato M, Stutts MJ, Boucher RC, Van Scott MR. Chinet TC, et al. Biochem Biophys Res Commun. 1997 Jan 13;230(2):470-5. doi: 10.1006/bbrc.1996.5939. Biochem Biophys Res Commun. 1997. PMID: 9016805
Deregulated expression and function of CFTR and Cl- secretion after activation of the Ras and Src/PyMT pathways in Caco-2 cells.
Davenport SE, Mergey M, Cherqui G, Boucher RC, Gespach C, Gabriel SE. Davenport SE, et al. Biochem Biophys Res Commun. 1996 Dec 13;229(2):663-72. doi: 10.1006/bbrc.1996.1861. Biochem Biophys Res Commun. 1996. PMID: 8954955
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