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Deciphering the nuclear bile acid receptor FXR paradigm.
Modica S, Gadaleta RM, Moschetta A. Modica S, et al. Among authors: gadaleta rm. Nucl Recept Signal. 2010 Nov 19;8:e005. doi: 10.1621/nrs.08005. Nucl Recept Signal. 2010. PMID: 21383957 Free PMC article. Review.
Tissue-specific actions of FXR in metabolism and cancer.
Gadaleta RM, Cariello M, Sabbà C, Moschetta A. Gadaleta RM, et al. Biochim Biophys Acta. 2015 Jan;1851(1):30-9. doi: 10.1016/j.bbalip.2014.08.005. Epub 2014 Aug 17. Biochim Biophys Acta. 2015. PMID: 25139561 Review.
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders.
Pellicciari R, Passeri D, De Franco F, Mostarda S, Filipponi P, Colliva C, Gadaleta RM, Franco P, Carotti A, Macchiarulo A, Roda A, Moschetta A, Gioiello A. Pellicciari R, et al. Among authors: gadaleta rm. J Med Chem. 2016 Oct 13;59(19):9201-9214. doi: 10.1021/acs.jmedchem.6b01126. Epub 2016 Oct 4. J Med Chem. 2016. PMID: 27652492
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy.
Celestini V, Tezil T, Russo L, Fasano C, Sanese P, Forte G, Peserico A, Lepore Signorile M, Longo G, De Rasmo D, Signorile A, Gadaleta RM, Scialpi N, Terao M, Garattini E, Cocco T, Villani G, Moschetta A, Grossi V, Simone C. Celestini V, et al. Among authors: gadaleta rm. Cell Death Dis. 2018 Feb 14;9(2):231. doi: 10.1038/s41419-018-0336-0. Cell Death Dis. 2018. PMID: 29445193 Free PMC article.
34 results