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Recognizing diversity in public preferences: the use of preference sub-groups in cost-effectiveness analysis.
Sculpher M, Gafni A. Sculpher M, et al. Health Econ. 2001 Jun;10(4):317-24. doi: 10.1002/hec.592. Health Econ. 2001. PMID: 11400254
Public preferences are typically incorporated into cost-effectiveness analyses (CEA) on the basis of the average health state utilities of a sample of individuals drawn from the general public. The cost-effectiveness of a programme is then assessed on an 'all-or-not …
Public preferences are typically incorporated into cost-effectiveness analyses (CEA) on the basis of the average health state utilities of …
NICE methodological guidelines and decision making in the National Health Service in England and Wales.
Gafni A, Birch S; NICE; National Health Service. Gafni A, et al. Pharmacoeconomics. 2003;21(3):149-57. doi: 10.2165/00019053-200321030-00001. Pharmacoeconomics. 2003. PMID: 12558466
The analytical basis of the guidelines is a comparison of the costs and consequences of new and existing methods of dealing with particular conditions using the incremental cost-effectiveness ratio. We explain why information on the costs and consequences of a parti …
The analytical basis of the guidelines is a comparison of the costs and consequences of new and existing methods of dealing with part …
Measuring Public Preferences for Health Outcomes and Expenditures in a Context of Healthcare Resource Re-Allocation.
Krucien N, Pelletier-Fleury N, Gafni A. Krucien N, et al. Pharmacoeconomics. 2019 Mar;37(3):407-417. doi: 10.1007/s40273-018-0751-1. Pharmacoeconomics. 2019. PMID: 30499065 Clinical Trial.
METHOD: In a sample of 200 participants providing 4200 observations, we compared four versions of the preference-elicitation instrument using a range of indicators. ...CONCLUSION: This validated instrument can now be used in a larger representative sample to …
METHOD: In a sample of 200 participants providing 4200 observations, we compared four versions of the preference-elicitation instrume …
The additive utility assumption of the QALY model revisited.
Gandjour A, Gafni A. Gandjour A, et al. J Health Econ. 2010 Mar;29(2):325-8; author reply 329-31. doi: 10.1016/j.jhealeco.2009.11.001. Epub 2009 Nov 11. J Health Econ. 2010. PMID: 20004033
Quality-adjusted life years are valid representations of the preferences of individuals for health outcomes only under a set of restrictive assumptions. ...Journal of Health Economics 27 (5), 1237-1249] presented a new test for AUI, the test for generalized marginal …
Quality-adjusted life years are valid representations of the preferences of individuals for health outcomes only under a set of restr …
On the margins of health economics: a response to 'resolving NICE'S nasty dilemma'.
Birch S, Gafni A. Birch S, et al. Health Econ Policy Law. 2015 Apr;10(2):183-93. doi: 10.1017/S1744133114000462. Health Econ Policy Law. 2015. PMID: 25747196
In a 2011 article published in this journal, Baker et al. set out to resolve a nasty dilemma for NICE by reconciling two approaches for determining whether adopting a new intervention would increase total health gains produced from available resources and hen …
In a 2011 article published in this journal, Baker et al. set out to resolve a nasty dilemma for NICE by reconciling two appro …
Uncertainty and the decision maker: assessing and managing the risk of undesirable outcomes.
Gafni A, Walter S, Birch S. Gafni A, et al. Health Econ. 2013 Nov;22(11):1287-94. doi: 10.1002/hec.2883. Epub 2012 Dec 26. Health Econ. 2013. PMID: 23280702
., a 'quadrant effect') and its magnitude by its location within the quadrant (i.e., 'within quadrant effect'). By explicitly defining the loss function, the process of accepting (or rejecting) a new program becomes transparent. We illustrate the approach using a
., a 'quadrant effect') and its magnitude by its location within the quadrant (i.e., 'within quadrant effect'). By explicitly definin …
The biggest bang for the buck or bigger bucks for the bang: the fallacy of the cost-effectiveness threshold.
Birch S, Gafni A. Birch S, et al. J Health Serv Res Policy. 2006 Jan;11(1):46-51. doi: 10.1258/135581906775094235. J Health Serv Res Policy. 2006. PMID: 16378532
On the contrary, the practical consequence of using the ICER approach is shown to be an increase in health care expenditures, or "bigger bucks for making a bang", without any evidence of the bang being bigger (i.e. that this leads to an increase in benefits to the populati …
On the contrary, the practical consequence of using the ICER approach is shown to be an increase in health care expenditures, or "bigger buc …
Incremental cost-effectiveness ratios (ICERs): the silence of the lambda.
Gafni A, Birch S. Gafni A, et al. Soc Sci Med. 2006 May;62(9):2091-100. doi: 10.1016/j.socscimed.2005.10.023. Epub 2005 Dec 1. Soc Sci Med. 2006. PMID: 16325975
Double discounting of QALYs.
MacKeigan LD, Gafni A, O'Brien BJ. MacKeigan LD, et al. Health Econ. 2003 Feb;12(2):165-9. doi: 10.1002/hec.718. Health Econ. 2003. PMID: 12563665
Quality-adjusted life-years (QALYs) calculated from time tradeoff (TTO) based preferences have a time preference component. To impose a conventional discount rate on these implicitly discounted QALYs introduces some degree of double discounting. The purpose of this …
Quality-adjusted life-years (QALYs) calculated from time tradeoff (TTO) based preferences have a time preference component. To impose …
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