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Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride.
Premkumar A, Wilson L, Ewart GD, Gage PW. Premkumar A, et al. Among authors: gage pw. FEBS Lett. 2004 Jan 16;557(1-3):99-103. doi: 10.1016/s0014-5793(03)01453-4. FEBS Lett. 2004. PMID: 14741348
Validation of coronavirus E proteins ion channels as targets for antiviral drugs.
Wilson L, Gage P, Ewart G. Wilson L, et al. Among authors: gage p. Adv Exp Med Biol. 2006;581:573-8. doi: 10.1007/978-0-387-33012-9_104. Adv Exp Med Biol. 2006. PMID: 17037600 Free PMC article. No abstract available.
SARS coronavirus E protein forms cation-selective ion channels.
Wilson L, McKinlay C, Gage P, Ewart G. Wilson L, et al. Among authors: gage p. Virology. 2004 Dec 5;330(1):322-31. doi: 10.1016/j.virol.2004.09.033. Virology. 2004. PMID: 15527857 Free PMC article.
Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication.
Wilson L, Gage P, Ewart G. Wilson L, et al. Among authors: gage p. Virology. 2006 Sep 30;353(2):294-306. doi: 10.1016/j.virol.2006.05.028. Epub 2006 Jul 3. Virology. 2006. PMID: 16815524 Free PMC article.
., Gage, P., Ewart, G., 2004. SARS coronavirus E protein forms cation-selective ion channels. Virology 330(1), 322-331). We now report that three other E proteins also form cation-selective ion channels. ...
., Gage, P., Ewart, G., 2004. SARS coronavirus E protein forms cation-selective ion channels. Virology 330(1), 322-331). We now repor …
The cytotoxic plant protein, beta-purothionin, forms ion channels in lipid membranes.
Hughes P, Dennis E, Whitecross M, Llewellyn D, Gage P. Hughes P, et al. Among authors: gage p. J Biol Chem. 2000 Jan 14;275(2):823-7. doi: 10.1074/jbc.275.2.823. J Biol Chem. 2000. PMID: 10625613
The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator.
Dulhunty A, Gage P, Curtis S, Chelvanayagam G, Board P. Dulhunty A, et al. Among authors: gage p. J Biol Chem. 2001 Feb 2;276(5):3319-23. doi: 10.1074/jbc.M007874200. Epub 2000 Oct 16. J Biol Chem. 2001. PMID: 11035031
Functional asymmetry of the conserved cystine loops in alphabetagamma GABA A receptors revealed by the response to GABA activation and drug potentiation.
Tierney ML, Luu T, Gage PW. Tierney ML, et al. Among authors: gage pw. Int J Biochem Cell Biol. 2008;40(5):968-79. doi: 10.1016/j.biocel.2007.10.029. Epub 2007 Nov 6. Int J Biochem Cell Biol. 2008. PMID: 18083058
The neuroactive steroids alphaxalone and pregnanolone increase the conductance of single GABAA channels in newborn rat hippocampal neurons.
Gaul S, Ozsarac N, Liu L, Fink RH, Gage PW. Gaul S, et al. Among authors: gage pw. J Steroid Biochem Mol Biol. 2007 Apr;104(1-2):35-44. doi: 10.1016/j.jsbmb.2006.09.042. Epub 2007 Jan 24. J Steroid Biochem Mol Biol. 2007. PMID: 17254775
The Mu class glutathione transferase is abundant in striated muscle and is an isoform-specific regulator of ryanodine receptor calcium channels.
Abdellatif Y, Liu D, Gallant EM, Gage PW, Board PG, Dulhunty AF. Abdellatif Y, et al. Among authors: gage pw. Cell Calcium. 2007 May;41(5):429-40. doi: 10.1016/j.ceca.2006.08.004. Epub 2006 Oct 4. Cell Calcium. 2007. PMID: 17023043
Conductance of recombinant GABA (A) channels is increased in cells co-expressing GABA(A) receptor-associated protein.
Everitt AB, Luu T, Cromer B, Tierney ML, Birnir B, Olsen RW, Gage PW. Everitt AB, et al. Among authors: gage pw. J Biol Chem. 2004 May 21;279(21):21701-6. doi: 10.1074/jbc.M312806200. Epub 2004 Mar 8. J Biol Chem. 2004. PMID: 15007071
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