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Early signaling dynamics of the epidermal growth factor receptor.
Reddy RJ, Gajadhar AS, Swenson EJ, Rothenberg DA, Curran TG, White FM. Reddy RJ, et al. Among authors: gajadhar as. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3114-9. doi: 10.1073/pnas.1521288113. Epub 2016 Feb 29. Proc Natl Acad Sci U S A. 2016. PMID: 26929352 Free PMC article.
System level dynamics of post-translational modifications.
Gajadhar AS, White FM. Gajadhar AS, et al. Curr Opin Biotechnol. 2014 Aug;28:83-7. doi: 10.1016/j.copbio.2013.12.009. Epub 2014 Jan 15. Curr Opin Biotechnol. 2014. PMID: 24441143 Free PMC article. Review.
Phosphotyrosine signaling analysis in human tumors is confounded by systemic ischemia-driven artifacts and intra-specimen heterogeneity.
Gajadhar AS, Johnson H, Slebos RJ, Shaddox K, Wiles K, Washington MK, Herline AJ, Levine DA, Liebler DC, White FM; Clinical Proteomic Tumor Analysis Consortium. Gajadhar AS, et al. Cancer Res. 2015 Apr 1;75(7):1495-503. doi: 10.1158/0008-5472.CAN-14-2309. Epub 2015 Feb 10. Cancer Res. 2015. PMID: 25670172 Free PMC article.
ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.
Agnihotri S, Burrell K, Buczkowicz P, Remke M, Golbourn B, Chornenkyy Y, Gajadhar A, Fernandez NA, Clarke ID, Barszczyk MS, Pajovic S, Ternamian C, Head R, Sabha N, Sobol RW, Taylor MD, Rutka JT, Jones C, Dirks PB, Zadeh G, Hawkins C. Agnihotri S, et al. Cancer Discov. 2014 Oct;4(10):1198-213. doi: 10.1158/2159-8290.CD-14-0157. Epub 2014 Aug 6. Cancer Discov. 2014. PMID: 25100205 Free PMC article.
Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.
Agnihotri S, Gajadhar AS, Ternamian C, Gorlia T, Diefes KL, Mischel PS, Kelly J, McGown G, Thorncroft M, Carlson BL, Sarkaria JN, Margison GP, Aldape K, Hawkins C, Hegi M, Guha A. Agnihotri S, et al. Among authors: gajadhar as. J Clin Invest. 2012 Jan;122(1):253-66. doi: 10.1172/JCI59334. Epub 2011 Dec 12. J Clin Invest. 2012. PMID: 22156195 Free PMC article.
16 results