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Galectin-1 suppresses experimental colitis in mice.
Santucci L, Fiorucci S, Rubinstein N, Mencarelli A, Palazzetti B, Federici B, Rabinovich GA, Morelli A. Santucci L, et al. Gastroenterology. 2003 May;124(5):1381-94. doi: 10.1016/s0016-5085(03)00267-1. Gastroenterology. 2003. PMID: 12730878
The aim of the present study was to evaluate the therapeutic effects of galectin-1 on T-helper cell type 1-mediated experimental colitis induced by intrarectal administration of 2,4,6-trinitrobenzene sulfonic acid (TNBS) in mice. METHODS: …
The aim of the present study was to evaluate the therapeutic effects of galectin-1 on T-helper cell type 1-mediated …
Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis.
Fernandez-Perez R, Lopez-Santalla M, Sánchez-Domínguez R, Alberquilla O, Gutiérrez-Cañas I, Juarranz Y, Bueren JA, Garin MI. Fernandez-Perez R, et al. Front Immunol. 2021 Jun 28;12:687443. doi: 10.3389/fimmu.2021.687443. eCollection 2021. Front Immunol. 2021. PMID: 34262567 Free PMC article.
Several studies have demonstrated that administration of recombinant galectin-1 suppressed experimental colitis by modulating adaptive immune responses altering the fate and phenotype of T cells. ...We found that galectin-1 deficie …
Several studies have demonstrated that administration of recombinant galectin-1 suppressed experimental colit