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Galectin-3 drives oligodendrocyte differentiation to control myelin integrity and function.
Pasquini LA, Millet V, Hoyos HC, Giannoni JP, Croci DO, Marder M, Liu FT, Rabinovich GA, Pasquini JM. Pasquini LA, et al. Cell Death Differ. 2011 Nov;18(11):1746-56. doi: 10.1038/cdd.2011.40. Epub 2011 May 13. Cell Death Differ. 2011. PMID: 21566659 Free PMC article.
In spite of considerable progress in dissecting their role within lymphoid organs, their functions within the inflamed CNS remain elusive. Here, we investigated the role of galectin-glycan interactions in the control of oligodendrocyte (OLG) differe
In spite of considerable progress in dissecting their role within lymphoid organs, their functions within the inflamed CNS remain elu …
Extracellular Galectin-3 Induces Accelerated Oligodendroglial Differentiation Through Changes in Signaling Pathways and Cytoskeleton Dynamics.
Thomas L, Pasquini LA. Thomas L, et al. Mol Neurobiol. 2019 Jan;56(1):336-349. doi: 10.1007/s12035-018-1089-6. Epub 2018 Apr 27. Mol Neurobiol. 2019. PMID: 29704198
Galectin-3 (Gal-3) is a chimeric protein structurally composed of unusual tandem repeats of proline and short glycine-rich segments fused onto a carbohydrate recognition domain. Our studies have previously demonstrated that Gal-3 drives oligo
Galectin-3 (Gal-3) is a chimeric protein structurally composed of unusual tandem repeats of proline and short glycine-r