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Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia.
Crossan GP, van der Weyden L, Rosado IV, Langevin F, Gaillard PHL, McIntyre RE; Sanger Mouse Genetics Project; Gallagher F, Kettunen MI, Lewis DY, Brindle K, Arends MJ, Adams DJ, Patel KJ. Crossan GP, et al. Among authors: gallagher f. Nat Genet. 2011 Feb;43(2):147-52. doi: 10.1038/ng.752. Epub 2011 Jan 16. Nat Genet. 2011. PMID: 21240276 Free PMC article.
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.
Gallagher FA, Kettunen MI, Hu DE, Jensen PR, Zandt RI, Karlsson M, Gisselsson A, Nelson SK, Witney TH, Bohndiek SE, Hansson G, Peitersen T, Lerche MH, Brindle KM. Gallagher FA, et al. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19801-6. doi: 10.1073/pnas.0911447106. Epub 2009 Nov 10. Proc Natl Acad Sci U S A. 2009. PMID: 19903889 Free PMC article.
231 results