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E2F transcription factor-1 modulates expression of glutamine metabolic genes in mouse embryonic fibroblasts and uterine sarcoma cells.
Huber K, Giralt A, Dreos R, Michenthaler H, Geller S, Barquissau V, Ziegler DV, Tavernari D, Gallart-Ayala H, Krajina K, Jonas K, Ciriello G, Ivanisevic J, Prokesch A, Pichler M, Fajas L. Huber K, et al. Biochim Biophys Acta Mol Cell Res. 2024 Jun;1871(5):119721. doi: 10.1016/j.bbamcr.2024.119721. Epub 2024 Apr 3. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 38580088 Free article.
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia.
Laurila PP, Wohlwend M, Imamura de Lima T, Luan P, Herzig S, Zanou N, Crisol B, Bou-Sleiman M, Porcu E, Gallart-Ayala H, Handzlik MK, Wang Q, Jain S, D'Amico D, Salonen M, Metallo CM, Kutalik Z, Eichmann TO, Place N, Ivanisevic J, Lahti J, Eriksson JG, Auwerx J. Laurila PP, et al. Nat Aging. 2022 Dec;2(12):1159-1175. doi: 10.1038/s43587-022-00309-6. Epub 2022 Dec 16. Nat Aging. 2022. PMID: 37118545
ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH.
Liu YJ, Kimura M, Li X, Sulc J, Wang Q, Rodríguez-López S, Scantlebery AML, Strotjohann K, Gallart-Ayala H, Vijayakumar A, Myers RP, Ivanisevic J, Houtkooper RH, Subramanian GM, Takebe T, Auwerx J. Liu YJ, et al. J Hepatol. 2025 Feb;82(2):174-188. doi: 10.1016/j.jhep.2024.08.009. Epub 2024 Aug 22. J Hepatol. 2025. PMID: 39181211 Free PMC article.
96 results